Table 1:

Significant results of a t test for comparison of DTI parameters between patients and controls

Quantity	Contrast	Whole White Matter Skeleton^{^a}
Quantity	Contrast	Voxels	%	Threshold t
FA	Controls > LHON	7310	5.5	1.54
	Controls > OPA1-DOA^{^b}	40,197	30.3	1.02
	Controls > pure OPA1-DOA^{^c}	19,006	14.3	1.18
MD	LHON > controls	652	0.5	0.95
	OPA1-DOA > controls^{^b}	38,789	29.2	2.33
	Pure OPA1-DOA > controls^{^c}	19,170	14.5	1.13

↵a Results are expressed as the number of voxels within the TBSS skeleton showing significant differences, along with the percentage so affected.
↵b All patients included.
↵c Three cases with OPA1 plus are excluded.