Table 1:

Clinical and radiologic characteristics of patients treated with rtPA (N = 52)

	rtPA-Treated (N = 52)	P Value (Where Appropriate)
Clinical characteristics
Age (yr) (mean ± SEM)	55.6 ± 1.4
Male/female	34:18
Admission GCS (median) (IQR)	8.5 (9.0)
Radiographic characteristics
ICH location (%)
Basal ganglia	8 (15.4)
Caudate	2 (3.8)
Thalamus	25 (48.1)
Lobar	6 (11.5)
Primary IVH	11 (21.2)
Admission Graeb score²¹ (median) (IQR)	7 (3)
Total IVH volume (cm³) (median) (IQR)
t0	31.94 (34.1)
t1	12.84 (26.23)	.001 (t1 vs t0)^{^a}
t2	4.86 (14.49)	.001 (t2 vs t0)^{^a}
Total IVH HU counts (mean ± SEM)
t0	52.14 ± 0.59
t1	50.11 ± 0.63	.002 (t1 vs t0)^{^a}
t2	45.05 ± 0.71	.001 (t2 vs t0)^{^a}
Total CSF HU counts (mean ± SEM)
t0	12.37 ± 0.37
t1	11.77 ± 0.37	.18 (t1 vs t0)
t2	11.30 ± 0.33	.01 (t2 vs t0)^{^a}
Hematoma (ICH) volume (cm³) (median) (IQR)
t0	7.0 (10.11)
t1	5.35 (9.39)	.001 (t1 vs t0)^{^a}
t2	5.04 (8.06)	.001 (t2 vs t0)^{^a}
Hematoma (ICH) HU counts (mean ± SEM)
t0	55.06 ± 0.82
t1	54.78 ± 0.86	.74 (t1 vs t0)
t2	48.42 ± 0.84	.001 (t2 vs t0)^{^a}
Change in IVH volume (cm³) (median) (IQR)
Days 2–4 (t1–t0)	−15.36 (18.13)	.001^{^a}
Days 5–9 (t2–t0)	−17.72 (21.84)	.001^{^a}
Change in ICH volume (cm³) (median) (IQR)
Days 2–4 (t1–t0)	−1.59 (3.22)	.001^{^a}
Days 5–9 (t2–t0)	−1.66 (3.8)	.001^{^a}
Change in IVH HU counts (mean ± SEM)
Days 2–4 (t1–t0)	−2.03 ± 0.62	.002^{^a}
Days 5–9 (t2–t0)	−6.89 ± 0.74	.001^{^a}
Change in ICH HU counts (mean ± SEM)
Days 2–4 (t1–t0)	−0.28 ± 0.86	.74
Days 5–9 (t2–t0)	−6.65 ± 1.12	.001^{^a}