Regression model demonstrating association between lobar microbleeds and CSF amyloid-β level (log transformed)
| CSF Aβ (Log Transformed) | Coefficient (95% CI) | P Value |
|---|---|---|
| No. of lobar microbleeds | ||
| 1 | −0.005 (−0.057 to 0.047) | .85 |
| 2 | −0.030 (−0.12 to 0.056) | .49 |
| 3 | −0.30 (−0.48 to −0.12) | .001 |
| >3 | −0.18 (−0.29 to −0.068) | .002 |
| Age | −0.007 (−0.0098 to −0.0041) | <.001 |
| Male sex | −0.013 (−0.055 to −0.030) | .57 |
| Years of education | 0.003 (−0.0046 to 0.011) | .40 |
| APOE4 | −0.23 (−0.28 to −0.19) | <.001 |
| APOE2 | 0.059 (−0.022 to 0.14) | .15 |
| MCI | −0.078 (−0.13 to −0.028) | .002 |
| AD | −0.26 (−0.33 to −0.19) | <.001 |
| History of hypertension | −0.011 (−0.052 to 0.031) | .61 |
Note:—MCI indicates mild cognitive impairment.