Demographic information on participants in the current studya

Healthy (n = 25)MCI (n = 18)AD (n = 7)
% Female64%55%71%
Education (yr)15.6 (3.6)14.9 (1.2)13.2 (1.2)
Age at MRI (yr)87.4 (5.0)88.3 (5.4)85.2 (4.4)
Age at death (yr)90.3 (4.7)91.1 (5.4)88.7 (4.9)
Years between MRI and death2.8 (1.3)2.8 (1.2)3.6 (1.5)
Entorhinal cortex thickness1.50 (0.30)1.49 (0.27)1.40 (0.41)
EC tangle density8.9 (6.2)12.8 (10.3)20.1 (12.9)
EC amyloid-β load5.5 (5.1)7.1 (5.1)7.5 (4.9)
  • Note:—MCI indicates mild cognitive impairment.

  • a All values are expressed as mean (SD).