Summary of the meta-analytic pooled proportions for nondiagnostic results, inconclusive results, and malignancy on CNB

No. of StudiesTotal No. of CasesSummary EstimateTrim-and-Fill Estimate
Pooled Proportion (95% CI)P Value for HeterogeneityaI2bNo. of Missing StudiesAdjusted Pooled Proportion (95% CI)
Nondiagnostic results618361.8% (0.4%–3.2%)<.0194.6%20.8% (−0.8%–2.5%)
Inconclusive results6183625.1% (15.4%–34.9%)<.0195.8%0
Malignancy6183618.9% (8.4%–29.5%)<.0198.3%115.6% (4.4%–26.8%)
  • a P value by the Cochran Q method to test the heterogeneity of the pooled data, with P < .05 indicating substantial heterogeneity.

  • b Higgins index for heterogeneity (0%–40%, might not be important; 30%–60%, may represent moderate heterogeneity; 50%–90%, may represent substantial heterogeneity; 75%–100%, may represent considerable heterogeneity).