Table 1:

Univariate analysis of IAUC histogram parameters as predictors of OS and PFS in the unmethylated and methylated MGMT subgroups.

Survival/Parameters	Unmethylated MGMT (n = 51)			Methylated MGMT (n = 37)
Survival/Parameters	Cutoff Value	HR (95% CI)	P Value^{^a}	Cutoff Value	HR (95% CI)	P Value^{^a}
OS
IAUC30_mean	≥10.9	3.04 (1.28–7.21)	.008	≥15.1	0.60 (0.17–2.14)	.429
IAUC60_mean	≥28.4	3.48 (1.20–10.14)	.015	≥32.0	0.42 (0.16–1.14)	.079
PFS
IAUC30_mean	≥10.9	2.60 (1.23–5.50)	.010	≥15.1	0.52 (0.18–1.56)	.238
IAUC60_mean	≥32.6	2.15 (1.14–4.05)	.015	≥32.8	0.24 (0.22–1.28)	.155

Note:—HR indicates hazard ratio.
↵a Calculated from the log-rank test.