Patient demographics
| Characteristic | Overall (%) (N = 235) | Detectable Calcification in Either ICA (%) (n = 200) | No Detectable Calcification in Either ICA (%) (n = 35) | P Value | Detectable (>0%) Stenosis in Either ICA (%) (n = 91) | No Detectable (0%) Stenosis in Either ICA (%) (n = 144) | P Value |
|---|---|---|---|---|---|---|---|
| Age | 71.7 ± 14.5 | 74.9 ± 12.1 | 53.2 ± 13.3 | <.0001 | 76.9 ± 10.6 | 68.4 ± 15.7 | <.0001 |
| Female | 118 (50.2) | 100 (50.0) | 18 (51.40) | .88 | 45 (49.5) | 73 (50.7) | .85 |
| Race | .91 | .35 | |||||
| White | 210 (89.4) | 179 (89.5) | 31 (88.6) | 78 (85.7) | 132 (91.7) | ||
| Black | 13 (5.5) | 11 (5.5) | 2 (5.7) | 7 (7.7) | 6 (4.2) | ||
| Other | 12 (5.1) | 10 (5.0) | 2 (5.7) | 6 (6.6) | 6 (4.2) | ||
| Atrial fibrillation | 46 (19.6) | 44 (22.0) | 2 (5.7) | .02 | 20 (22.0) | 26 (18.1) | .46 |
| Coronary artery disease | 50 (21.3) | 47 (23.5) | 3 (8.6) | .05 | 26 (28.6) | 24 (16.7) | .03 |
| Carotid artery stenosis | 8 (3.4) | 8 (4.0) | 0 (0) | .61 | 4 (4.4) | 4 (2.8) | .71 |
| Diabetes mellitus | 69 (29.4) | 64 (32.0) | 5 (14.3) | .03 | 38 (41.8) | 31 (21.5) | .001 |
| Hypertension | 163 (69.4) | 149 (74.5) | 14 (40.0) | <.0001 | 77 (84.6) | 86 (59.7) | <.0001 |
| Dyslipidemia | 120 (51.1) | 113 (56.5) | 7 (20.0) | <.0001 | 57 (62.6) | 63 (43.8) | .01 |
| NIHSS score | .16 | .39 | |||||
| 1 | 49 (20.9) | 37 (18.5) | 12 (34.3) | 14 (15.4) | 35 (24.3) | ||
| 2 | 57 (24.3) | 51 (25.5) | 6 (17.1) | 22 (24.2) | 35 (24.3) | ||
| 3 | 36 (15.3) | 30 (15.0) | 6 (17.1) | 15 (16.5) | 21 (14.6) | ||
| 4 | 93 (39.6) | 82 (41.0) | 11 (31.4) | 40 (44.0) | 53 (36.8) | ||
| Prior stroke | 71 (30.2) | 66 (33.0) | 5 (14.3) | .03 | 30 (33.0) | 41 (28.5) | .46 |
| Peripheral vascular disease | 17 (7.2) | 15 (7.5) | 2 (5.7) | 1.00 | 8 (8.8) | 9 (6.3) | .46 |
| Active tobacco use | 20 (8.5) | 16 (8.0) | 4 (11.4) | .51 | 8 (8.8) | 12 (8.3) | .90 |
| IV tPA administered | 33 (14.0) | 23 (11.5) | 10 (28.6) | .01 | 8 (8.8) | 25 (17.4) | .07 |
| Valvular disease | 6 (2.6) | 6 (3.0) | 0 (0) | .60 | 2 (2.2) | 4 (2.8) | 1.00 |