Independent t test and receiver operating characteristic curve analysis of low-/high-grade glioma
| MTRasym(3.5ppm) | Low-Grade Gliomas (n = 28) | High-Grade Gliomas (n = 14) | P Value | Area Under the Curvea | Optimal Threshold (%) | Sensitivity (%) | Specificity (%) |
|---|---|---|---|---|---|---|---|
| Reader 1 | 2.65% ± 0.20 | 3.74% ± 0.17 | .001 | .813 (.675, .95) | 3.11 | 92.9 | 71.4 |
| Reader 2 | 2.63% ± 0.18 | 3.47% ± 0.16 | .004 | .770 (.623, .918) | 2.85 | 92.9 | 71.4 |
| Mean MTRasym(3.5ppm) | 2.64% ± 0.18 | 3.61% ± 0.155 | .002 | .791 (.650, .931) | 2.93 | 92.9 | 71.4 |
| Mean Ki-67 labeling index | 4.98% ± 1.02 (n = 24) | 24.15% ± 5.04 (n = 13) | .003 | .867 (.702, 1.00) | 6.5 | 84.6 | 83.3 |
↵a Data in parentheses are 95% CIs.