Table 1:

Patient demographic and clinical characteristicsa

Aggressive TumorNonaggressive TumorP Value
No.610
Volume change ratio14.4 ± 21.0 (−2.18–17.2)0.463 ± 1.135 (−1.40–3.78).003
Doubling time (mo)5.77 ± 4.03 (0.73–10.8)NA
Age at first operation (yr)54.3 ± 9.945.8 ± 24.3.713
Location of tumor (ratio of clival chordoma to all)3/68/10.299b
Postsurgical RT radiation dose (Gy)72.4 ± 33.5 (n = 4)74.2 ± 10.9 (n = 7).927
Ratio of patients with postsurgical RT to all4/69/10.518b
Time from first operation to first follow-up MRI (mo)62.8 ± 53.371.4 ± 76.2>.99
Time between the 2 follow-up MRIs (mo)9.1 ± 5.218.3 ± 12.5.022
No. of surgical resections at first follow-up MRI2.00 ± 0.891.10 ± 0.32.056
Sex (M/F)5:17:3>.99b
Histopathology (ratio of classic chordoma to all chordomas)6/65/10.093b
Mean ADC (×10−3 × mm2/s)1.055 ± 0.298 (0.78–1.37)1.622 ± 0.139 (1.34–1.65)<.001
Tumor volume (× 103 × mm3)21.2 ± 37.4 (0–60.4)3.44 ± 2.38 (0–7.46).492
  • Note:—NA indicates not applicable.

  • a Numbers in the table represent mean ± SD. The numbers in parentheses indicate the 95% CIs.

  • b P value was calculated by the Fisher exact test because the data were categoric.