Summary of patient characteristics and MR imaging and volumetric parameters for the cohort of patients with MGBM considered in the study

MGBM Cohort
Patient characteristics
    No. of patients (censored)97 (7)
    Age (median) (range) (yr)64 (23–83)
    Sex (percentage) (age range)49 F, 50.52% (25–82 yr)
46 M, 49.48% (23–83 yr)
    Survival (median) (range) (mo)7.39 (0.13–56.08)
    Type of resection (percentage)55 MSR (56.70%)
42 B (43.30%)
    Type of treatment (percentage)63 CT + RT (64.95%)
6 RT alone (6.19%)
5 CT alone (5.15%)
23 No treatment (23.71%)
MRI characteristics
    Pixel spacing (mean) (range) (mm)0.78 (0.39–1.17)
    Slice thickness (mean) (range) (mm)1.55 (1.00–2.00)
    No. of slices (mean) (range)171 (84–248)
Volumetric parametersa
    Tumor volume (mean) (range) (cm3)24.04 (0.20–115.79)
28.55 (0.39–125.59)
    CE volume (mean) (range) (cm3)14.60 (0.20–64.35)
17.92 (0.39–73.18)
    Necrotic volume (mean) (range) (cm3)9.43 (0.00–63.43)
10.63 (0.00–63.44)
    CE rim width (mean) (range) (cm)0.53 (0.15–1.17)
0.59 (0.19–1.24)
    Maximum diameter (mean) (range) (cm)4.59 (1.07–9.15)
6.95 (2.42–14.75)
    Total surface (mean) (range) (cm2)54.31 (2.32–183.63)
69.53 (5.01–212.20)
    Surface regularity (mean) (range)0.62 (0.15–0.93)
NA
  • Note:—MSR indicates maximal safe resection; NA, not applicable; CT, chemotherapy; RT, radiation therapy; B, biopsy.

  • a There are 2 volumetric parameters: those measured for the lesion with the largest volume (first row) and those computed for the aggregated tumor (second row).