Table 3:

Independent predictors of favorable outcome; successful, excellent reperfusion; and first-pass effecta

OR (95%CI)P Valueb
Favorable outcome
    Age0.72 (0.58–0.91)b.005
    Admission NIHSS score0.86 (0.81–0.91)c<.001
    Prestroke mRS ≥10.37 (0.17–0.78).009
    Intravenous rtPA2.61 (1.42–4.78).002
    Site of occlusion.026
        M1 MCA1.00 (ref)
        M2 MCA0.81 (0.31–2.09).66
        T-car0.65 (0.30–1.41).27
        Tandem0.49 (0.21–1.14).098
        Vertebrobasilar0.15 (0.05–0.49).002
    General anesthesia0.36 (0.17–0.76).008
    Procedural time (min)
        Onset to imaging0.87 (0.77–0.97)d.017
        Imaging to groin puncture0.67 (0.52–0.90)d.007
Successful reperfusion
    Current smoking0.36 (0.18–0.72).004
    ASPECTS1.25 (1.08–1.45)c.003
Excellent reperfusion
    Age1.26 (1.04–1.54).018
    Antiplatelet drugs2.31 (1.24–4.32).009
    Blood glucose (mmol/L)0.87 (0.77–0.97).012
    Site of occlusion<.001
        M1 MCA1.00 (ref)
        M2 MCA0.86 (0.35–2.14).75
        T-car0.38 (0.18–0.79).010
        Tandem0.38 (0.16–0.91).030
        Vertebrobasilar2.55 (1.11–5.85).027
Sofia catheter
    >5F0.38 (0.17–0.83).015
    >6F1.00 (ref)
First-pass effect
    Age1.48 (1.16–1.90).002
    Site of occlusion<.001
        M1 MCA1.00 (ref)
        M2 MCA0.75 (0.32–1.75)
        T-car0.11 (0.03–0.38)
        Tandem0.13 (0.03–0.60)
        Vertebrobasilar2.46 (1.07–5.75)
    Intravenous rtPA2.01 (1.09–3.71).024

  • Note:—ref indicates reference; T-Car, occlusion of carotid terminus.

  • ↵a Factors included in multivariate analysis of favorable outcome: age, hta, previous stroke or TIA, systolic BP, admission NIHSS score and ASPECTS, prestroke mRS ≥1, intravenous rtPA, general anesthesia, delay in imaging-to-groin puncture, site of occlusion, and the Sofia catheter. Factors included in multivariate model of successful reperfusion: age, current smoking, admission ASPECTS, site of occlusion, intravenous rtPA, etiology, delay in onset to imaging. Factors included in multivariate analysis of excellent reperfusion: age, sex, current smoking, antiplatelet use, glycemia, admission ASPECTS, site of occlusion, intravenous rtPA, and the Sofia catheter. Factors included in multivariate analysis of first-pass effect: age, current smoking, previous stroke or TIA, antiplatelet use, glycemia, admission NIHSS score and ASPECTS, prestroke mRS ≥1, site of occlusion. and intravenous rtPA.

  • ↵b Per 10-year increase.

  • ↵c Per 1-point increase.

  • ↵d Per 1-hour increase.