Clinical characteristics of the study groupsa
| Controls (n = 29) | INSVM (n = 32) | P | |
|---|---|---|---|
| Maternal age (yr) | 33.7 ± 4.2 | 32.4 ± 5.5 | .32 |
| Birth weight (g) | 3414 ± 517 | 3406 ± 553 | .96 |
| Gestational age at birth (wk) | 39.8 ± 0.9 | 39.8 ± 1.2 | .81 |
| Gestational age at MRI (wk) | 27.7 ± 0.9 | 27.7 ± 0.9 | .91 |
| Lateral ventricular widtha | 4.6 ± 1.4 | 10.6 ± 1.1 | <.01b |
| Fetus sex | .02d | ||
| Male | 58.6% (17) | 87.5% (28) | |
| Female | 41.4% (12) | 12.5% (4) | |
| Laterality of ventriculomegaly | |||
| Bilateral | – | 34.4% (11) | |
| Unilateral left | – | 34.4% (11) | |
| Unilateral right | – | 31.2% (10) | |
| Evolution of lateral ventricular widthc | |||
| Regressive | – | 25% (8) | |
| Stable | – | 75% (24) | |
| Progressive | – | 0% (0) | |
| Classification according to atrial width | |||
| Mild (10.0–11.9 mm) | – | 84.3% (27) | |
| Moderate (12.0–13.9 mm) | – | 16.7% (5) |
Note:— – indicates that these characteristics do not apply for the control group.
↵a Comparison of clinical characteristics between the control and case cohort. Results are expressed as means or percentage and number of subjects as appropriate.
↵b Measurement of the more dilated lateral ventricle by ultrasound at diagnosis.
↵c Evolution of lateral ventricular width until term of pregnancy.
↵d Significant (≤.05).