Gadolinium deposition in skin samples from patients with NSF (adapted from Roberts et al34)
Lead Author | No. of Patients with NSF | Range of Gadolinium Levels (μg/g) | No. of Controls | Range of Gadolinium Levels (μg/g) | Comment |
---|---|---|---|---|---|
Inductively Coupled Mass Spectrometry (ICP-MS) Techniques | |||||
High et al7 | 5 | 4.8–106 | 1 | 0 | Limits of detection not provided |
Khurana et al35 | 6 | 57.2–717.8 | 2 | ||
Infant Foreskin | 0.0 (reported as ppm) | ||||
2 Multiple Sclerosis Patients | 0.1 | 3-5 Gadolinium MRIs 1 MS patient marginal renal function | |||
Scleroderma Patient | 0.2 | ||||
Christensen et al36 | 13 | Affected skin 6.3–348.7 | 13 | 2 − 0.1 | 2 with previous GBCA administration |
Unaffected skin 0.6–68.2 | 11 below detectable range | ||||
Roberts et al34 | 1? | 14.5 | 61 GBCA MRIs, eGFR >59 mL/min/1.73 m2 |
Note:—? indicates NSF diagnosis was not confirmed.