Diagnostic accuracy of imaging biomarkers on CTA in determining patients tested for SARS-CoV-2 (n = 106)
| Sensitivity (95% CI) | Specificity (95% CI) | PPV (95% CI) | NPV (95% CI) | |
|---|---|---|---|---|
| Presence of GGO | 75% (56–87) | 81% (71–88) | 58% (41–74) | 90% (79–95) |
| Focal GGO | 46% (29–64) | 90% (81–95) | 62% (39–81) | 82% (72–89) |
| Bilateral GGO | 57% (37–75) | 82% (72–89) | 53% (35–71) | 84% (73–91) |
| Peripheral GGO | 68% (49–82) | 88% (79–94) | 68% (48–83) | 88% (79–94) |
| COVID-19-typical/in-determinatea | 64% (46–79) | 92% (84–94) | 77% (50–92) | 88% (74–95) |
Note:—PPV indicates positive predictive value; NPV, negative predictive value.
↵a COVID-19-typical alone gave a low sensitivity (36%) and was excluded from further analysis. COVID-19 CT imaging definitions are listed in On-line Table 1.