Prediction of TTP in PCNSLs according to tumor habitat, ADC, and CBVa
| Combination of Clinical, Conventional Imaging Predictors, and Tumor Habitats | Combined Clinical and Conventional Predictors | Tumor Habitats | Clinical Predictors Only | Conventional Imaging Predictors Only | |
|---|---|---|---|---|---|
| C-index | 0.73 | 0.71 | 0.65 | 0.68 | 0.63 |
| 95% CI | 0.67–0.80 | 0.54–0.78 | 0.52–0.78 | 0.54–0.82 | 0.50–0.76 |
| P value | Reference | .01 | .012 | .81 | .62 |
↵a Combined clinical predictors were age, ECOG score, and mean serum LDH level; the conventional imaging predictor was the presence of atypical image findings. P value refers to the significance in the difference of the C-indices between the combined model and the single model assessed using “CompareC” (https://cran.r-project.org/web/packages/compareC/index.html) in the R statistical and computing software.