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Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.


AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

MY CONTENT

  • FELLOWS' JOURNAL CLUBPractice Perspectives
    You have access
    A Call to Improve the Visibility and Access of the American College of Radiology Practice Parameters in Neuroradiology: A Powerful Value Stream Enhancer for Both Neuroradiologists and Patients
    J.E. Jordan and A. Norbash
    American Journal of Neuroradiology February 2019, 40 (2) 213-216; DOI: https://doi.org/10.3174/ajnr.A5923

    The authors suggest that practitioners gain a high degree of familiarity with accessing practice parameters. Doing so will provide additional reference and access to the practice parameters when medical literature searches are undertaken or when questions arise regarding best practices. Such an approach will ensure that future neuroradiology clinical guidelines or technical standards documents are provided as broad an exposure as possible. This effort could enhance the visibility and accessibility of the quality of practice for neuroradiologists, provide needed clinical guidance to practice state-of-the-art neuroradiology/radiology, and ensure the visibility of our valuable contributions to both individual patient care and collective patient outcomes.

  • Functional
    Open Access
    Resting-State Functional Connectivity of the Middle Frontal Gyrus Can Predict Language Lateralization in Patients with Brain Tumors
    S. Gohel, M.E. Laino, G. Rajeev-Kumar, M. Jenabi, K. Peck, V. Hatzoglou, V. Tabar, A.I. Holodny and B. Vachha
    American Journal of Neuroradiology February 2019, 40 (2) 319-325; DOI: https://doi.org/10.3174/ajnr.A5932
  • FELLOWS' JOURNAL CLUBAdult Brain
    You have access
    A Deep Learning–Based Approach to Reduce Rescan and Recall Rates in Clinical MRI Examinations
    A. Sreekumari, D. Shanbhag, D. Yeo, T. Foo, J. Pilitsis, J. Polzin, U. Patil, A. Coblentz, A. Kapadia, J. Khinda, A. Boutet, J. Port and I. Hancu
    American Journal of Neuroradiology February 2019, 40 (2) 217-223; DOI: https://doi.org/10.3174/ajnr.A5926

    The purpose of this study was to develop a fast, automated method for assessing rescan need in motion-corrupted brain series. A deep learning–based approach was developed, outputting a probability for a series to be clinically useful. Comparison of this per-series probability with a threshold, which can depend on scan indication and reading radiologist, determines whether a series needs to be rescanned. The deep learning classification performance was compared with that of 4 technologists and 5 radiologists in 49 test series with low and moderate motion artifacts. Fast, automated deep learning–based image-quality rating can decrease rescan and recall rates, while rendering them technologist-independent. It was estimated that decreasing rescans and recalls from the technologists' values to the values of deep learning could save hospitals $24,000/scanner/year.

  • EDITOR'S CHOICEHead & Neck
    Open Access
    Treatment Response Prediction of Nasopharyngeal Carcinoma Based on Histogram Analysis of Diffusional Kurtosis Imaging
    N. Tu, Y. Zhong, X. Wang, F. Xing, L. Chen and G. Wu
    American Journal of Neuroradiology February 2019, 40 (2) 326-333; DOI: https://doi.org/10.3174/ajnr.A5925

    Thirty-six patients with an initial diagnosis of locoregionally advanced nasopharyngeal carcinoma and diffusional kurtosis imaging acquisitions before and after neoadjuvant chemotherapy were enrolled. Patients were divided into respond-versus-nonrespond groups after neoadjuvant chemotherapy and residual-versus-nonresidual groups after radiation therapy. Receiver operating characteristic analysis indicated that setting pre-D50th = 0.875 x 10-3 mm2/s as the cutoff value could result in optimal diagnostic performance for neoadjuvant chemotherapy response prediction (area under the curve = 0.814, sensitivity = 0.70, specificity = 0.92), while the post-K90th = 1.035 (area under the curve = 0.829, sensitivity = 0.78, specificity = 0.72) was optimal for radiation therapy response prediction. Histogram analysis of diffusional kurtosis imaging may potentially predict the neoadjuvant chemotherapy and short-term radiation therapy response in locoregionally advanced nasopharyngeal carcinoma.

  • EDITOR'S CHOICEAdult Brain
    Open Access
    Improving the Quality of Synthetic FLAIR Images with Deep Learning Using a Conditional Generative Adversarial Network for Pixel-by-Pixel Image Translation
    A. Hagiwara, Y. Otsuka, M. Hori, Y. Tachibana, K. Yokoyama, S. Fujita, C. Andica, K. Kamagata, R. Irie, S. Koshino, T. Maekawa, L. Chougar, A. Wada, M.Y. Takemura, N. Hattori and S. Aoki
    American Journal of Neuroradiology February 2019, 40 (2) 224-230; DOI: https://doi.org/10.3174/ajnr.A5927

    Forty patients with MS were prospectively included and scanned (3T) to acquire synthetic MR imaging and conventional FLAIR images. Synthetic FLAIR images were created with the SyMRI software. Acquired data were divided into 30 training and 10 test datasets. A conditional generative adversarial network was trained to generate improved FLAIR images from raw synthetic MR imaging data using conventional FLAIR images as targets. The peak signal-to-noise ratio, normalized root mean square error, and the Dice index of MS lesion maps were calculated for synthetic and deep learning FLAIR images against conventional FLAIR images, respectively. Lesion conspicuity and the existence of artifacts were visually assessed. The peak signal-to-noise ratio and normalized root mean square error were significantly higher and lower, respectively, in generated-versus-synthetic FLAIR images in aggregate intracranial tissues and all tissue segments. The Dice index of lesion maps and visual lesion conspicuity were comparable between generated and synthetic FLAIR images. Using deep learning, the authors conclude that they improved the synthetic FLAIR image quality by generating FLAIR images that have contrast closer to that of conventional FLAIR images and fewer granular and swelling artifacts, while preserving the lesion contrast.

  • Head & Neck
    Open Access
    Contrast-Enhanced 3D-FLAIR Imaging of the Optic Nerve and Optic Nerve Head: Novel Neuroimaging Findings of Idiopathic Intracranial Hypertension
    E. Golden, R. Krivochenitser, N. Mathews, C. Longhurst, Y. Chen, J.-P.J. Yu and T.A. Kennedy
    American Journal of Neuroradiology February 2019, 40 (2) 334-339; DOI: https://doi.org/10.3174/ajnr.A5937
  • Adult Brain
    Open Access
    Effect of Gadolinium on the Estimation of Myelin and Brain Tissue Volumes Based on Quantitative Synthetic MRI
    T. Maekawa, A. Hagiwara, M. Hori, C. Andica, T. Haruyama, M. Kuramochi, M. Nakazawa, S. Koshino, R. Irie, K. Kamagata, A. Wada, O. Abe and S. Aoki
    American Journal of Neuroradiology February 2019, 40 (2) 231-237; DOI: https://doi.org/10.3174/ajnr.A5921
  • Pediatrics
    Open Access
    Cavum Septum Pellucidum in the General Pediatric Population and Its Relation to Surrounding Brain Structure Volumes, Cognitive Function, and Emotional or Behavioral Problems
    M.H.G. Dremmen, R.H. Bouhuis, L.M.E. Blanken, R.L. Muetzel, M.W. Vernooij, H.E. Marroun, V.W.V. Jaddoe, F.C. Verhulst, H. Tiemeier and T. White
    American Journal of Neuroradiology February 2019, 40 (2) 340-346; DOI: https://doi.org/10.3174/ajnr.A5939
  • Adult Brain
    You have access
    FDG-PET and MRI in the Evolution of New-Onset Refractory Status Epilepticus
    T. Strohm, C. Steriade, G. Wu, S. Hantus, A. Rae-Grant and M. Larvie
    American Journal of Neuroradiology February 2019, 40 (2) 238-244; DOI: https://doi.org/10.3174/ajnr.A5929
  • Pediatrics
    Open Access
    MR Imaging Scoring System for White Matter Injury after Deep Medullary Vein Thrombosis and Infarction in Neonates
    K.L. Benninger, N.L. Maitre, L. Ruess and J.A. Rusin
    American Journal of Neuroradiology February 2019, 40 (2) 347-352; DOI: https://doi.org/10.3174/ajnr.A5940

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