- Absence of the Susceptibility Vessel Sign with Cancer-Associated Hypercoagulability-Related Stroke
Cancer-associated hypercoagulability-related stroke is presumably caused by fibrin-predominant thrombi and is associated with the absence of the susceptibility vessel sign (sensitivity of 90%/specificity of 78%/ likelihood ratio of 4.06). This is in contradistinction to cardioembolic erythrocyte-predominant thrombi, which demonstrate hypointense signal on T2-weighted gradient-recalled echo images (susceptibility vessel sign).
- Temporal Changes on Postgadolinium MR Vessel Wall Imaging Captures Enhancement Kinetics of Intracranial Atherosclerotic Plaques and Aneurysms
MR VWI in patients with symptomatic intracranial atherosclerotic disease plaques and aneurysms showed contrast accumulation beyond the early-phase (5–15 min) into the delayed phase (20–30 min). This nonspecific enhancement may indicate focal inflammation, neoangiogenesis, and/or increased permeability. The authors advocate postcontrast imaging soon after contrast administration to optimize diagnostic accuracy.
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