- The Interpeduncular Angle: A Practical and Objective Marker for the Detection and Diagnosis of Intracranial Hypotension on Brain MRI
MRIs of 30 patients with intracranial hypotension and 30 age-matched controls were evaluated by 2 neuroradiologists for classic findings of intracranial hypotension and the interpeduncular angle. Group analysis was performed with a Student t test, and receiver operating characteristic analysis was used to identify an ideal angle threshold to maximize sensitivity and specificity. The interpeduncular angle had excellent interobserver reliability (intraclass correlation coefficient value = 0.833) and was significantly lower in the intracranial hypotension group compared with the control group (25.3° versus 56.3°). There was significant correlation between the interpeduncular angle and the presence of brain stem slumping. With a threshold of 40.5°, sensitivity and specificity were 80% and 96.7%, respectively.