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Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.

AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

MY CONTENT

  • Ultra-High-Field MRI/Imaging of Epilepsy/Demyelinating Diseases/Inflammation/Infection
    Multicenter Automated Central Vein Sign Detection Performs as Well as Manual Assessment for the Diagnosis of Multiple Sclerosis
    A.R. Manning, V. Letchuman, M.L. Martin, E. Gombos, T. Robert-Fitzgerald, Q. Cao, P. Raza, C.M. O’Donnell, B. Renner, L. Daboul, P. Rodrigues, M. Ramos, J. Derbyshire, C. Azevedo, A. Bar-Or, E. Caverzasi, P.A. Calabresi, B.A.C. Cree, L. Freeman, R.G. Henry, E.E. Longbrake, J. Oh, N. Papinutto, D. Pelletier, R.D. Samudralwar, S. Suthiphosuwan, M.K. Schindler, M. Bilello, J.W. Song, E.S. Sotirchos, N.L. Sicotte, O. Al-Louzi, A.J. Solomon, D.S. Reich, D. Ontaneda, P. Sati, R.T. Shinohara and the NAIMS Cooperative
    American Journal of Neuroradiology March 2025, 46 (3) 620-626; DOI: https://doi.org/10.3174/ajnr.A8510
  • Ultra-High-Field MRI/Imaging of Epilepsy/Demyelinating Diseases/Inflammation/Infection
    DSC MR Perfusion at 7T MRI: An Initial Single-Center Study for Validity and Practicability
    Clare E. Buntrock, Ceren Dinçer, Onur Tuncer, Matthew White, Alexis Swensen, Mark Folkertsma and Can Özütemiz
    American Journal of Neuroradiology March 2025, 46 (3) 627-634; DOI: https://doi.org/10.3174/ajnr.A8513
  • Ultra-High-Field MRI/Imaging of Epilepsy/Demyelinating Diseases/Inflammation/Infection
    Assessment of Trigeminal Nerve Root Demyelination in Patients with Primary Trigeminal Neuralgia Using Macromolecular Proton Fraction Imaging
    Elena A. Filimonova, Anton A. Pashkov, Vasily L. Yarnykh, Maria I. Schukina, Boris A. Zaitsev, Azniv V. Martirosyan, Galina I. Moysak and Jamil A. Rzaev
    American Journal of Neuroradiology March 2025, 46 (3) 602-610; DOI: https://doi.org/10.3174/ajnr.A8545
  • Ultra-High-Field MRI/Imaging of Epilepsy/Demyelinating Diseases/Inflammation/Infection
    Diffusion- and Tractography-Based Characterization of Tissue Damage Within and Surrounding Paramagnetic Rim Lesions in Multiple Sclerosis
    Maryam Mohebbi, Jack A. Reeves, Dejan Jakimovski, Alexander Bartnik, Niels Bergsland, Fahad Salman, Ferdinand Schweser, Bianca Weinstock-Guttman, Robert Zivadinov and Michael G. Dwyer
    American Journal of Neuroradiology March 2025, 46 (3) 611-619; DOI: https://doi.org/10.3174/ajnr.A8524
  • Ultra-High-Field MRI/Imaging of Epilepsy/Demyelinating Diseases/Inflammation/Infection
    Quantitative Susceptibility Mapping in Adults with Persistent Postconcussion Symptoms after Mild Traumatic Brain Injury: An Exploratory Study
    Tiffany K. Bell, Muhammad Ansari, Julie M. Joyce, Leah J. Mercier, David G. Gobbi, Richard Frayne, Chantel Debert and Ashley D. Harris
    American Journal of Neuroradiology February 2025, 46 (2) 435-442; DOI: https://doi.org/10.3174/ajnr.A8454
  • EDITOR'S CHOICEUltra-High-Field MRI/Imaging of Epilepsy/Demyelinating Diseases/Inflammation/Infection
    Dynamic Expansion and Contraction of Multiple Sclerosis T2-Weighted Hyperintense Lesions Are Present below the Threshold of Visual Perception
    Darin T. Okuda, Tatum M. Moog, Morgan McCreary, Kevin Shan, Kasia Zubkow, Braeden D. Newton, Alexander D. Smith, Mahi A. Patel, Katy W. Burgess and Christine Lebrun-Frénay
    American Journal of Neuroradiology February 2025, 46 (2) 443-450; DOI: https://doi.org/10.3174/ajnr.A8453

    Recognition of longitudinal imaging changes of MS lesions has substantial implications for clinical management, but changes may remain below the resolution of human perception. In this study, the authors demonstrated that T2-weighted hyperintense lesions undergo dynamic change on MRI, with predominantly enlarging or contracting characteristics, more frequently seen in untreated individuals.

  • EDITOR'S CHOICEUltra-High-Field MRI/Imaging of Epilepsy/Demyelinating Diseases/Inflammation/Infection
    Macro- and Microstructural White Matter Differences in Neurologic Postacute Sequelae of SARS-CoV-2 Infection
    Erin E. O’Connor, Rosangela Salerno-Goncalves, Nikita Rednam, Rory O’Brien, Peter Rock, Andrea R. Levine and Thomas A. Zeffiro
    American Journal of Neuroradiology December 2024, 45 (12) 1910-1918; DOI: https://doi.org/10.3174/ajnr.A8481

    In this cross-sectional study, SARS-CoV-2 infection effects on GM/WM volume, WM microstructure, cognitive performance, and peripheral cytokine concentrations were investigated. The study found that the NeuroPASC group had larger global and regional (prefrontal cortex and hippocampus) cerebral WM volume, more self-reported PASC symptoms, more headaches, lower psychometric performance, widespread higher mean kurtosis in WM microstructure, and different cytokine concentration profiles compared with controls. The authors conclude that immune dysregulation following SARS-CoV-2 infection might result in cerebral WM macrostructural and microstructural injury causing NeuroPASC clinical signs and symptoms.

  • Ultra-High-Field MRI/Imaging of Epilepsy/Demyelinating Diseases/Inflammation/Infection
    Prevalence of Rathke Cleft and Other Incidental Pituitary Gland Findings on Contrast-Enhanced 3D Fat-Saturated T1 MPRAGE at 7T MRI
    Mikael Mir, Nathaniel P. Miller, Matthew White, Wendy Elvandahl, Ayca Ersen Danyeli and Can Özütemiz
    American Journal of Neuroradiology November 2024, 45 (11) 1811-1818; DOI: https://doi.org/10.3174/ajnr.A8393
  • Ultra-High-Field MRI/Imaging of Epilepsy/Demyelinating Diseases/Inflammation/Infection
    Low-Field (64 mT) Portable MRI for Rapid Point-of-Care Diagnosis of Dissemination in Space in Patients Presenting with Optic Neuritis
    Timothy Reynold Lim, Suradech Suthiphosuwan, Jonathan Micieli, Reza Vosoughi, Raphael Schneider, Amy W. Lin, Yingming Amy Chen, Alexandra Muccilli, James J. Marriott, Daniel Selchen, Shobhit Mathur, Jiwon Oh and Aditya Bharatha
    American Journal of Neuroradiology November 2024, 45 (11) 1819-1825; DOI: https://doi.org/10.3174/ajnr.A8395
  • FELLOWS' JOURNAL CLUBUltra-High-Field MRI/Imaging of Epilepsy/Demyelinating Diseases/Inflammation/Infection
    Glial Fibrillary Acidic Protein Astrocytopathy: Review of Pathogenesis, Imaging Features, and Radiographic Mimics
    Dhruv Shetty, Sneh Brahmbhatt, Amit Desai, Girish Bathla, Suyash Mohan, Vivek Gupta, Neetu Soni, Prasanna Vibhute and Amit Agarwal
    American Journal of Neuroradiology October 2024, 45 (10) 1394-1402; DOI: https://doi.org/10.3174/ajnr.A8236

    Glial fibrillary acidic protein (GFAP) astrocytopathy is a CNS autoimmune inflammatory disorder characterized by specific antibodies targeting the intracellular filament protein in mature astrocytes. Neuroimaging findings include linear perivascular enhancement in the white matter extending in a radial pattern, periependymal enhancement, longitudinally extensive cord signal changes, intramedullary enhancement, optic neuritis, and papillitis.

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