- Multisite Benchmark Study for Standardized Relative CBV in Untreated Brain Metastases Using the DSC-MRI Consensus Acquisition Protocol
This multisite study found that the consensus DSC-MRI acquisition protocol confirmed the utility of standardized rCBV (srCBV) to identify biologically active, treatment-naïve brain metastases as distinguished from normal-appearing white matter and GBM. The data demonstrated that brain metastases of different primary origins have srCBV values that in general are significantly greater than normal-appearing white matter but significantly lower than srCBV for GBM.
- Dynamic Expansion and Contraction of Multiple Sclerosis T2-Weighted Hyperintense Lesions Are Present below the Threshold of Visual Perception
Recognition of longitudinal imaging changes of MS lesions has substantial implications for clinical management, but changes may remain below the resolution of human perception. In this study, the authors demonstrated that T2-weighted hyperintense lesions undergo dynamic change on MRI, with predominantly enlarging or contracting characteristics, more frequently seen in untreated individuals.
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