- Brain Maturation Patterns on Normalized FLAIR MR Imaging in Children and Adolescents
Studies to date have shown signal maturation patterns in the pediatric population using various sequences. However, there is a paucity of information about brain maturation patterns of FLAIR signal intensities across the pediatric range. Additionally, intensities vary widely across FLAIR MR imaging scanners. A FLAIR intensity standardization algorithm would be helpful to normalize intensity across large data sets, allowing comparison of FLAIR intensity in different regions and individuals.
- Longitudinal Changes in Cerebral Perfusion, Perivascular Space Volume, and Ventricular Volume in a Healthy Cohort Undergoing a Spaceflight Analog
Cerebral physiologic changes occur in response to the unique physiologic stressor of altered gravity, including a decrease in global perfusion and increase in ventricular/PVS volumes during spaceflight analog and subsequent reversal during recovery. The findings of this study contribute to our understanding of the relationships among the circulatory, glymphatic, and ventricular systems of the brain.
- Resisted Inspiration Improves Visualization of CSF-Venous Fistulas in Spontaneous Intracranial Hypotension
This retrospective cohort of patients with observed or suspected CSF-venous fistula identified during standard maximum suspended inspiration CT myelography were rescanned using resisted inspiration and the Valsalva maneuver. Visibility of the CSF-venous fistula was greatest during resisted inspiration in most of the cases.
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