- Radiation Necrosis in Pediatric Patients with Brain Tumors Treated with Proton Radiotherapy
The authors performed a retrospective study on 60 consecutive pediatric patients with primary brain tumors treated with proton radiation therapy. Thirty-one percent of patients developed radiation necrosis with a median time to development of 5 months. They conclude that patients with pediatric brain tumors treated with proton radiation therapy demonstrate a high incidence of radiation necrosis and a short time to development of necrosis. Multiple small areas of necrosis are frequently identified on imaging.
- Disrupted Global and Regional Structural Networks and Subnetworks in Children with Localization-Related Epilepsy
Impaired structural connectivity affecting global and regional networks and subnetworks in children with localization-related epilepsy was demonstrated. The impairment in structural connectivity was extensive despite the apparent focality of the seizure disorders.
- Susceptibility-Weighted Imaging in Pediatric Arterial Ischemic Stroke: A Valuable Alternative for the Noninvasive Evaluation of Altered Cerebral Hemodynamics
Based on imaging findings in 24 pediatric patients,the authors conclude that SWI-DTI mismatch predicts progression in pediatric arterial ischemic stroke. SWI-hyperintense signal is not useful for predicting the development of malignant edemabut SWI should be routinely added to the neuroimaging diagnostic protocol of pediatric arterial ischemic stroke.
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