- Dynamic Expansion and Contraction of Multiple Sclerosis T2-Weighted Hyperintense Lesions Are Present below the Threshold of Visual Perception
Recognition of longitudinal imaging changes of MS lesions has substantial implications for clinical management, but changes may remain below the resolution of human perception. In this study, the authors demonstrated that T2-weighted hyperintense lesions undergo dynamic change on MRI, with predominantly enlarging or contracting characteristics, more frequently seen in untreated individuals.
- Hemodynamic Characteristics in Ruptured and Unruptured Intracranial Aneurysms: A Prospective Cohort Study Utilizing the AneurysmFlow Tool
A DSA-based flow quantification tool (AneurysmFlow) was used to measure blood flow vectors and velocities after contrast injection. Complex flow patterns were shown to be common in ruptured aneurysms and those with daughter sacs. Lowest mean aneurysm flow amplitude in the dome and daughter sacs indicated pathophysiologic changes linked to rupture. Also, hypertension, bifurcation location, and irregular shape of unruptured aneurysm were found to be independent rupture risk factors.
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