- The Differentiation between Progressive Disease and Treatment-Induced Effects with Perfusion-Weighted Arterial Spin-Labeling in High-Grade Gliomas
In this retrospective, single-center cohort study, 141 patients (173 lesions) with a new or increasing contrast-enhancing lesion after radiotherapy with or without chemotherapy were assessed with ASL perfusion. Although ASL performed poorly in differentiating progressive disease from treatment-induced effects in high-grade gliomas within 6 months after radiation therapy, it showed fair performance after this period.