- Glial Fibrillary Acidic Protein Astrocytopathy: Review of Pathogenesis, Imaging Features, and Radiographic Mimics
Glial fibrillary acidic protein (GFAP) astrocytopathy is a CNS autoimmune inflammatory disorder characterized by specific antibodies targeting the intracellular filament protein in mature astrocytes. Neuroimaging findings include linear perivascular enhancement in the white matter extending in a radial pattern, periependymal enhancement, longitudinally extensive cord signal changes, intramedullary enhancement, optic neuritis, and papillitis.
- Myelographic Techniques for the Localization of CSF-Venous Fistulas: Updates in 2024
This is an updated comprehensive review of the various myelographic techniques that can be used to identify CSF-venous fistulas. The authors discuss the advantages and disadvantages of each and describe provocative maneuvers that may improve the conspicuity of CVFs.
- Absence of the Susceptibility Vessel Sign with Cancer-Associated Hypercoagulability-Related Stroke
Cancer-associated hypercoagulability-related stroke is presumably caused by fibrin-predominant thrombi and is associated with the absence of the susceptibility vessel sign (sensitivity of 90%/specificity of 78%/ likelihood ratio of 4.06). This is in contradistinction to cardioembolic erythrocyte-predominant thrombi, which demonstrate hypointense signal on T2-weighted gradient-recalled echo images (susceptibility vessel sign).
- Risk of Hemorrhagic Transformation after Mechanical Thrombectomy without versus with IV Thrombolysis for Acute Ischemic Stroke: A Systematic Review and Meta-analysis of Randomized Clinical Trials
This systematic review and meta-analysis evaluated the risk of intracerebral hemorrhage, and its subtypes associated with mechanical thrombectomy with or without IV thrombolysis for the treatment of acute ischemic stroke due to large-vessel occlusion. The analysis showed that the overall risk of symptomatic intracerebral hemorrhage was comparable between mechanical thrombectomy with IV thrombolysis and mechanical thrombectomy alone.
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