Abstract
SUMMARY: Fifteen patients with intradural spinal lesions were examined with an optimized dynamic contrast-enhanced MR perfusion sequence at 1.5T and 3T. SNR and mean contrast-to-noise ratio were better on 3T compared with 1.5T (P ≤ .05). The goodness of fit of the Tofts and Tofts extended pharmacokinetic models was similar between 1.5T and 3T. Thus, dynamic contrast-enhanced MR perfusion of intradural spinal canal lesions is technically feasible at 1.5T and 3T, with better image quality at 3T.
ABBREVIATIONS:
- AUC
- area under the curve
- CNR
- contrast-to-noise ratio
- DCE
- dynamic contrast-enhanced
- Ktrans
- volume transfer constant
- ve
- extravascular extracellular volume fraction
- vp
- blood plasma fraction
- © 2017 by American Journal of Neuroradiology
