Interscanner Variation in Brain MR Lesion Load Measurements in Multiple Sclerosis Using Conventional Spin-Echo, Rapid Relaxation-Enhanced, and Fast-FLAIR Sequences

aFrom the Neuroimaging Research Unit (M.F., M.A.R., M.P.S.) and Clinical Trials Unit (G.C.), Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan; Departments of Neurology (C.G., C.P.) and Neuroradiology (S.B.), Università “La Sapienza,” Rome; Department of Neurology (C.G.), San Camillo Hospital, Rome; Unit of Clinical Epidemiology and Trials (M.P.S.), Institute for Cancer Research, Genoa, Italy; and Division of Medical Physics (M.A.H.), University of Leicester, Leicester, UK.

aFrom the Neuroimaging Research Unit (M.F., M.A.R., M.P.S.) and Clinical Trials Unit (G.C.), Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan; Departments of Neurology (C.G., C.P.) and Neuroradiology (S.B.), Università “La Sapienza,” Rome; Department of Neurology (C.G.), San Camillo Hospital, Rome; Unit of Clinical Epidemiology and Trials (M.P.S.), Institute for Cancer Research, Genoa, Italy; and Division of Medical Physics (M.A.H.), University of Leicester, Leicester, UK.

aFrom the Neuroimaging Research Unit (M.F., M.A.R., M.P.S.) and Clinical Trials Unit (G.C.), Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan; Departments of Neurology (C.G., C.P.) and Neuroradiology (S.B.), Università “La Sapienza,” Rome; Department of Neurology (C.G.), San Camillo Hospital, Rome; Unit of Clinical Epidemiology and Trials (M.P.S.), Institute for Cancer Research, Genoa, Italy; and Division of Medical Physics (M.A.H.), University of Leicester, Leicester, UK.

aFrom the Neuroimaging Research Unit (M.F., M.A.R., M.P.S.) and Clinical Trials Unit (G.C.), Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan; Departments of Neurology (C.G., C.P.) and Neuroradiology (S.B.), Università “La Sapienza,” Rome; Department of Neurology (C.G.), San Camillo Hospital, Rome; Unit of Clinical Epidemiology and Trials (M.P.S.), Institute for Cancer Research, Genoa, Italy; and Division of Medical Physics (M.A.H.), University of Leicester, Leicester, UK.

aFrom the Neuroimaging Research Unit (M.F., M.A.R., M.P.S.) and Clinical Trials Unit (G.C.), Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan; Departments of Neurology (C.G., C.P.) and Neuroradiology (S.B.), Università “La Sapienza,” Rome; Department of Neurology (C.G.), San Camillo Hospital, Rome; Unit of Clinical Epidemiology and Trials (M.P.S.), Institute for Cancer Research, Genoa, Italy; and Division of Medical Physics (M.A.H.), University of Leicester, Leicester, UK.

aFrom the Neuroimaging Research Unit (M.F., M.A.R., M.P.S.) and Clinical Trials Unit (G.C.), Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan; Departments of Neurology (C.G., C.P.) and Neuroradiology (S.B.), Università “La Sapienza,” Rome; Department of Neurology (C.G.), San Camillo Hospital, Rome; Unit of Clinical Epidemiology and Trials (M.P.S.), Institute for Cancer Research, Genoa, Italy; and Division of Medical Physics (M.A.H.), University of Leicester, Leicester, UK.

aFrom the Neuroimaging Research Unit (M.F., M.A.R., M.P.S.) and Clinical Trials Unit (G.C.), Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan; Departments of Neurology (C.G., C.P.) and Neuroradiology (S.B.), Università “La Sapienza,” Rome; Department of Neurology (C.G.), San Camillo Hospital, Rome; Unit of Clinical Epidemiology and Trials (M.P.S.), Institute for Cancer Research, Genoa, Italy; and Division of Medical Physics (M.A.H.), University of Leicester, Leicester, UK.

aFrom the Neuroimaging Research Unit (M.F., M.A.R., M.P.S.) and Clinical Trials Unit (G.C.), Department of Neuroscience, Scientific Institute Ospedale San Raffaele, University of Milan; Departments of Neurology (C.G., C.P.) and Neuroradiology (S.B.), Università “La Sapienza,” Rome; Department of Neurology (C.G.), San Camillo Hospital, Rome; Unit of Clinical Epidemiology and Trials (M.P.S.), Institute for Cancer Research, Genoa, Italy; and Division of Medical Physics (M.A.H.), University of Leicester, Leicester, UK.