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Histopathologic Analysis of Foci of Signal Loss on Gradient-Echo T2*-Weighted MR Images in Patients with Spontaneous Intracerebral Hemorrhage: Evidence of Microangiopathy-Related Microbleeds

Franz Fazekas, Reinhold Kleinert, Gudrun Roob, Gertrude Kleinert, Peter Kapeller, Reinhold Schmidt and Hans-Peter Hartung
American Journal of Neuroradiology April 1999, 20 (4) 637-642;
Franz Fazekas
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Reinhold Kleinert
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Gudrun Roob
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Gertrude Kleinert
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Peter Kapeller
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Reinhold Schmidt
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Hans-Peter Hartung
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References

  1. ↵
    Caplan LR. Intracerebral hemorrhage. In: Tyler HR, Dawson D, eds. Current Neurology. Boston: Houghton-Mifflin; 1979;2:185–205
  2. Brott T, Thalinger K, Hertzberg V. Hypertension as a risk factor for spontaneous intracerebral hemorrhage. Stroke 1986;17:1078-1083
    Abstract/FREE Full Text
  3. ↵
    Wagle WA, Smith TW, Weiner M. Intracerebral hemorrhage caused by cerebral amyloid angiopathy: radiographic-pathologic correlation. AJNR Am J Neuroradiol 1984;5:171-176
    Abstract/FREE Full Text
  4. Vinters HA. Cerebral amyloid angiopathy: a critical review. Stroke 1987;2:311-324
  5. ↵
    Selekler K, Erzen C. Leukoaraiosis and intracerebral hematoma. Stroke 1989;20:1016-1020
    Abstract/FREE Full Text
  6. Inzitari D, Giordano GP, Ancona AL, Pracucci G, Mascalchi M, Amaducci L. Leukoaraiosis, intracerebral hemorrhage, and arterial hypertension. Stroke 1990;21:1419-1423
    Abstract/FREE Full Text
  7. ↵
    Atlas SW, Mark AS, Grossman RI, Gomori JM. Intracranial hemorrhage: gradient-echo MR imaging at 1.5 T: comparison with spin-echo imaging and clinical applications. Radiology 1988;168:803-807
    PubMedWeb of Science
  8. ↵
    Offenbacher H, Fazekas F, Schmidt R, Koch M, Fazekas G, Kapeller P. MR of cerebral abnormalities concomitant with primary intracerebral hematomas. AJNR Am J Neuroradiol 1996;17:573-578
    Abstract
  9. ↵
    Greenberg SM, Finkelstein SP, Schaefer PW. Petechial hemorrhages accompanying lobar hemorrhage: detection by gradient-echo MRI. Neurology 1996;46:1751-1754
    Abstract/FREE Full Text
  10. ↵
    Fazekas F, Kleinert R, Offenbacher H, et al. The morphologic correlate of incidental white matter hyperintensities on MR images. AJNR Am J Neuroradiol 1991;12:915-921
    Abstract/FREE Full Text
  11. ↵
    Fazekas F, Chawluk JB, Alavi A, Hurtig HI, Zimmerman RA. MR signal abnormalities at 1.5T in Alzheimer's dementia and normal aging. AJNR Am J Neuroradiol 1987;8:421-426
    Abstract/FREE Full Text
  12. ↵
    Vonsattel JPG, Myers RH, Hedley-Whyte ET, Ropper AH, Bird ED, Richardson EP Jr. Cerebral amyloid angiopathy without and with cerebral hemorrhages: a comparative histological study. Ann Neurol 1991;30:637-649
    CrossRefPubMedWeb of Science
  13. ↵
    Chan S, Kartha K, Yoon SS, Desmond DW, Hilal SK. Multifocal hypointense cerebral lesions on gradient-echo MR are associated with chronic hypertension. AJNR Am J Neuroradiol 1996;17:1821-1827
    Abstract
  14. Roob G, Schmidt R, Kapeller P, Lechner A, Hartung HP, Fazekas F. MRI evidence of past cerebral microbleeds in a healthy elderly population. Neurology 1999;52:991-994
    Abstract/FREE Full Text
  15. ↵
    Lammie GA, Brannan F, Slattery J, Warlow C. Nonhypertensive cerebral small-vessel disease: an autopsy study. Stroke 1997;28:2222-2229
    Abstract/FREE Full Text
  16. ↵
    The SPIRIT Study Group. A randomized trial of anticoagulants versus aspirin after cerebral ischemia of presumed arterial origin: the Stroke Prevention in Reversible Ischemia Trial (SPIRIT). Ann Neurol 1997;42:857-865
    CrossRefPubMedWeb of Science
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American Journal of Neuroradiology
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Histopathologic Analysis of Foci of Signal Loss on Gradient-Echo T2*-Weighted MR Images in Patients with Spontaneous Intracerebral Hemorrhage: Evidence of Microangiopathy-Related Microbleeds
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Franz Fazekas, Reinhold Kleinert, Gudrun Roob, Gertrude Kleinert, Peter Kapeller, Reinhold Schmidt, Hans-Peter Hartung
Histopathologic Analysis of Foci of Signal Loss on Gradient-Echo T2*-Weighted MR Images in Patients with Spontaneous Intracerebral Hemorrhage: Evidence of Microangiopathy-Related Microbleeds
American Journal of Neuroradiology Apr 1999, 20 (4) 637-642;

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Histopathologic Analysis of Foci of Signal Loss on Gradient-Echo T2*-Weighted MR Images in Patients with Spontaneous Intracerebral Hemorrhage: Evidence of Microangiopathy-Related Microbleeds
Franz Fazekas, Reinhold Kleinert, Gudrun Roob, Gertrude Kleinert, Peter Kapeller, Reinhold Schmidt, Hans-Peter Hartung
American Journal of Neuroradiology Apr 1999, 20 (4) 637-642;
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