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Research ArticleINTERVENTIONAL

Endovascular Management of Extracranial Carotid Artery Dissection Achieved Using Stent Angioplasty

Adel M. Malek, Randall T. Higashida, Constantine C. Phatouros, Todd E. Lempert, Philip M. Meyers, Wade S. Smith, Christopher F. Dowd and Van V. Halbach
American Journal of Neuroradiology August 2000, 21 (7) 1280-1292;
Adel M. Malek
aFrom the Departments of Radiology (A.M.M., R.T.H., C.C.P. T.E.L., P.M.M., C.F.D., V.V. H.), Division of Interventional Neurovascular Radiology, Neurosurgery (R.T.H., C.F.D., V.V.H.), and Neurology (W.S.S.), University of California, San Francisco, 94143, USA.
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Randall T. Higashida
aFrom the Departments of Radiology (A.M.M., R.T.H., C.C.P. T.E.L., P.M.M., C.F.D., V.V. H.), Division of Interventional Neurovascular Radiology, Neurosurgery (R.T.H., C.F.D., V.V.H.), and Neurology (W.S.S.), University of California, San Francisco, 94143, USA.
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Constantine C. Phatouros
aFrom the Departments of Radiology (A.M.M., R.T.H., C.C.P. T.E.L., P.M.M., C.F.D., V.V. H.), Division of Interventional Neurovascular Radiology, Neurosurgery (R.T.H., C.F.D., V.V.H.), and Neurology (W.S.S.), University of California, San Francisco, 94143, USA.
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Todd E. Lempert
aFrom the Departments of Radiology (A.M.M., R.T.H., C.C.P. T.E.L., P.M.M., C.F.D., V.V. H.), Division of Interventional Neurovascular Radiology, Neurosurgery (R.T.H., C.F.D., V.V.H.), and Neurology (W.S.S.), University of California, San Francisco, 94143, USA.
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Philip M. Meyers
aFrom the Departments of Radiology (A.M.M., R.T.H., C.C.P. T.E.L., P.M.M., C.F.D., V.V. H.), Division of Interventional Neurovascular Radiology, Neurosurgery (R.T.H., C.F.D., V.V.H.), and Neurology (W.S.S.), University of California, San Francisco, 94143, USA.
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Wade S. Smith
aFrom the Departments of Radiology (A.M.M., R.T.H., C.C.P. T.E.L., P.M.M., C.F.D., V.V. H.), Division of Interventional Neurovascular Radiology, Neurosurgery (R.T.H., C.F.D., V.V.H.), and Neurology (W.S.S.), University of California, San Francisco, 94143, USA.
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Christopher F. Dowd
aFrom the Departments of Radiology (A.M.M., R.T.H., C.C.P. T.E.L., P.M.M., C.F.D., V.V. H.), Division of Interventional Neurovascular Radiology, Neurosurgery (R.T.H., C.F.D., V.V.H.), and Neurology (W.S.S.), University of California, San Francisco, 94143, USA.
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Van V. Halbach
aFrom the Departments of Radiology (A.M.M., R.T.H., C.C.P. T.E.L., P.M.M., C.F.D., V.V. H.), Division of Interventional Neurovascular Radiology, Neurosurgery (R.T.H., C.F.D., V.V.H.), and Neurology (W.S.S.), University of California, San Francisco, 94143, USA.
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    fig 1.

    Simplified schematic illustration of the pathophysiologic process of carotid artery dissection proceeding from the acute stage to either spontaneous healing (1), formation of false lumen (2), residual stenosis of varying degree or complete occlusion (3), and formation of a pseudoaneurysm (4). A stent is used in cases that have not responded to medical therapy either to relieve a hemodynamically significant stenosis, to occlude a false lumen, or to serve as a scaffold to enable coil embolization of a wide-necked pseudoaneurysm

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    fig 2.

    A 45-year-old woman (patient 1) noted to have developed left hemiparesis after diagnostic angiography at an outside hospital. Head CT scan shows evidence of a previous focal infarct as well as diffuse edema in the right posterior frontal lobe (A). Digital subtraction angiography of the right common carotid artery reveals tapering of the right internal carotid artery, to a complete occlusion, with appearance consistent of dissection (B). Injection of the right external carotid artery (C) shows retrograde collateral flow through the right ophthalmic artery, with filling of the cavernous segment of the right ICA. Injection of the left internal carotid artery shows no significant flow across the anterior communicating artery (D)

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    fig 2.

    fig. 2 (continued). Treatment approach consisted of initial recanalization of the dissected right internal carotid artery achieved by entering the true lumen by using a Rapid Transit microcatheter and Instinct-10 microguidewire (arrowheads) (E), and advancing up to the cavernous portion of the right internal carotid artery (arrow) (F). Superselective injection shows a patent right middle and anterior cerebral artery (G). An 8-mm × 2-cm Wallstent was then deployed at the dissection site over a Stabilizer exchange microguidewire at the C2 level (H). The reconstitution of the lumen of the right internal carotid artery is shown by injection of the right common carotid artery (I), with resumption of intracranial perfusion (J)

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    fig 3.

    A 51-year-old man (patient 5) with a 10-day history of left-sided TIAs now presents with sudden onset of aphasia and right hemiparesis. Axial T1-weighted contrast-enhanced MR imaging shows a left frontal infarct (A). Digital subtraction angiography of the left common carotid artery showed progression of a left internal carotid dissection from a partial stenosis, 2 days prior, to a complete occlusion despite systemic anticoagulation (B). Digital subtraction angiography of the right common carotid artery revealed a dissection of the right internal carotid artery with an associated long-segment stenosis and an expansile pseudoaneurysm at the distal end (C). A Rapid Transit microcatheter was used to navigate the patent lumen of the right internal carotid artery and to deploy three Wallstents (6 mm × 45 mm, 7 mm × 20 mm, and 8 mm × 20 mm) in a tandem overlapping fashion with postdeployment balloon angioplasty (D). The procedure resulted in reconstitution of the normal lumen of the right internal carotid artery (E)

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    fig 4.

    An 83-year-old man (patient 4) with a history of aortic dissection, which was surgically repaired 10 years previously, presents with left hemispheric TIAs and episodes of aphasia. Digital subtraction angiography of the left common carotid artery outlines a chronic extensive dissection, with antegrade flow through the true lumen and retrograde flow in the false lumen down to the aorta, by virtue of the Venturi effect at the aortic arch (A, early injection; B, late injection). Two stents were placed in tandem overlapping fashion, followed by postdeployment angioplasty, resulting in a near-complete elimination of the retrograde flow in the now-reduced false lumen (C, D)

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    fig 5.

    A 51-year-old man (patient 3) developed sudden loss of vision in the left eye, a left Horner's syndrome, and orthostatic lightheadedness. Digital subtraction angiography with injection of the right common carotid artery shows intimal dissection of the right internal carotid artery in the high cervical region, with delineation of the true and false lumen (A, B). Injection of the left common carotid artery, which had evidence of dissection but was shown to be patent on an angiogram obtained 4 days earlier, now reveals complete left internal carotid artery occlusion (arrowhead) despite systemic anticoagulation (C). A Rapid Transit microcatheter was used to catheterize the true lumen, followed by deployment of a Wallstent (6 mm × 20 mm) in the proximal portion of the dissected segment (D). Persistent filling of the false lumen, however, required the tandem placement of two additional GFX stents (4 mm × 12 mm) in the petrous segment of the right internal carotid artery (E), with reconstitution of the normal luminal diameter (F)

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    TABLE 1:

    Summary of the clinical presentation, coexisting medical problems, duration of symptoms until treatment, presence and location of any infarct, etiology of the dissection, and indication for endovascular treatment

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    TABLE 2:

    Summary of the angiographic characteristics of the lesion, including location, presence of collaterals, method of treatment, stenosis, and complication related to treatment

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    TABLE 3:

    Outcome of treated patients immediately after the procedure and at latest follow–up

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American Journal of Neuroradiology
Vol. 21, Issue 7
1 Aug 2000
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Cite this article
Adel M. Malek, Randall T. Higashida, Constantine C. Phatouros, Todd E. Lempert, Philip M. Meyers, Wade S. Smith, Christopher F. Dowd, Van V. Halbach
Endovascular Management of Extracranial Carotid Artery Dissection Achieved Using Stent Angioplasty
American Journal of Neuroradiology Aug 2000, 21 (7) 1280-1292;

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Endovascular Management of Extracranial Carotid Artery Dissection Achieved Using Stent Angioplasty
Adel M. Malek, Randall T. Higashida, Constantine C. Phatouros, Todd E. Lempert, Philip M. Meyers, Wade S. Smith, Christopher F. Dowd, Van V. Halbach
American Journal of Neuroradiology Aug 2000, 21 (7) 1280-1292;
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  • 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery Disease: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American Stroke Association, American Association of Neuroscience Nurses, American Association of Neurological Surgeons, American College of Radiology, American Society of Neuroradiology, Congress of Neurological Surgeons, Society of Atherosclerosis Imaging and Prevention, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of NeuroInterventional Surgery, Society for Vascular Medicine, and Society for Vascular Surgery Developed in Collaboration With the American Academy of Neurology and Society of Cardiovascular Computed Tomography
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  • Guidelines for Prevention of Stroke in Patients With Ischemic Stroke or Transient Ischemic Attack: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association Council on Stroke: Co-Sponsored by the Council on Cardiovascular Radiology and Intervention: The American Academy of Neurology affirms the value of this guideline.
  • Guidelines for Prevention of Stroke in Patients With Ischemic Stroke or Transient Ischemic Attack: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association Council on Stroke: Co-Sponsored by the Council on Cardiovascular Radiology and Intervention: The American Academy of Neurology affirms the value of this guideline.
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