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Figures
- fig 1.
Case 2: 54-year-old man with a GBM.
A, Time course of the ΔR2* values of the GBM and normal white matter. The ΔR2*T1C values of the GBM are represented by solid squares and its gamma-fitted curve by a thick line; ΔR2*T1U is represented by solid circles and its gamma-fitted curve a thin line. The ΔR2*T1C values of normal white matter are represented by solid triangles and its gamma-fitted curve by a dashed line.
B, A stereotactic biopsy was performed before the MR study. A transaxial section of a contrast-enhanced T1-weighted (333/10/3) spin-echo image is shown on the left, the corresponding VT1U map is in the middle, and the VT1C map is on the right. The GBM shows nonhomogeneously dense contrast enhancement in the left frontotemporal lobe. Note that blood volume of the tumor is much more prominent on the VT1C map (arrow) than on the VT1U map. The qualitative analysis was rated as 1 in this case. The VT1U/VT1C ratio is 0.41.
- fig 2.
Case 5: 37-year-old man with a GBM who had previously undergone surgical resection, irradiation, and chemotherapy for a GBM of the right frontal lobe. Recently, a recurrent tumor was found on follow-up CT studies. A transaxial section of a contrast-enhanced T1-weighted spin-echo MR image (333/10/3) is shown on the left, a corresponding VT1U map is in the middle, and the VT1C map is on the right. The recurrent GBM shows dense contrast enhancement in the right frontal lobe, extending to the corpus callosum. Small, enhanced foci are also depicted in the left frontal lobe. Note that the lesion in the corpus callosum is depicted as an area of hypervascular blood volume on the VT1C map (arrow), and the blood volume of this lesion is similar to that of gray matter on the VT1U map, indicating the tumor blood volume is underestimated on the VT1U map. The qualitative analysis was rated as 1 in this case. The VT1U/VT1C ratio is 0.64
Tables
Results of quantitative and qualitative analysis of blood volume in GBMs
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