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Research ArticleBRAIN

Optic Pathway Glioma: Correlation of Imaging Findings with the Presence of Neurofibromatosis

Liora Kornreich, Susan Blaser, Michael Schwarz, Avinoam Shuper, Tal H. Vishne, Ian J. Cohen, Ricardo Faingold, Shalom Michovitz, Benjamin Koplewitz and Gadi Horev
American Journal of Neuroradiology November 2001, 22 (10) 1963-1969;
Liora Kornreich
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Susan Blaser
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Michael Schwarz
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Avinoam Shuper
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Tal H. Vishne
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Ian J. Cohen
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Ricardo Faingold
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Shalom Michovitz
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Benjamin Koplewitz
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Gadi Horev
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    fig 1.

    14-year-old boy with NF. A and B, Sagittal unenhanced (A) and coronal contrast-enhanced (B) T1-weighted MR images show typical findings of OPG in patients with NF: thickened retroorbital optic nerves and chiasm, with preservation of original contour. The tumor is small and homogeneous, without any cystic components

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    fig 2.

    4-year-old girl without NF. Axial contrast-enhanced T1-weighted image shows typical findings of optic glioma in patients with NF: a large mass, with cystic components, that does not respect the boundaries of the optic pathways. The temporal horns are enlarged, and the right middle cerebral artery courses in a fissure of the mass (arrow)

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    TABLE 1:

    Symptoms at presentation of children with OPG

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    TABLE 2:

    Involvement of optic tract by site

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    TABLE 3:

    Imaging features of OPG

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    TABLE 4:

    Size and extension of optic pathway glioma at follow-up

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American Journal of Neuroradiology: 22 (10)
American Journal of Neuroradiology
Vol. 22, Issue 10
1 Nov 2001
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Cite this article
Liora Kornreich, Susan Blaser, Michael Schwarz, Avinoam Shuper, Tal H. Vishne, Ian J. Cohen, Ricardo Faingold, Shalom Michovitz, Benjamin Koplewitz, Gadi Horev
Optic Pathway Glioma: Correlation of Imaging Findings with the Presence of Neurofibromatosis
American Journal of Neuroradiology Nov 2001, 22 (10) 1963-1969;

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Optic Pathway Glioma: Correlation of Imaging Findings with the Presence of Neurofibromatosis
Liora Kornreich, Susan Blaser, Michael Schwarz, Avinoam Shuper, Tal H. Vishne, Ian J. Cohen, Ricardo Faingold, Shalom Michovitz, Benjamin Koplewitz, Gadi Horev
American Journal of Neuroradiology Nov 2001, 22 (10) 1963-1969;
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Cited By...

  • ADC Histogram Analysis of Pediatric Low-Grade Glioma Treated with Selumetinib: A Report from the Pediatric Brain Tumor Consortium
  • Manifestations and Treatment of Adult-onset Symptomatic Optic Pathway Glioma in Neurofibromatosis Type 1
  • Optic Pathway Glioma and Cerebral Focal Abnormal Signal Intensity in Patients with Neurofibromatosis Type 1: Characteristics, Treatment Choices and Follow-up in 134 Affected Individuals and a Brief Review of the Literature
  • Risk of optic pathway glioma in children with neurofibromatosis type 1 and optic nerve tortuosity or nerve sheath thickening
  • Optical Coherence Tomography in the Diagnosis of Optic Pathway Gliomas
  • Neoplasms Associated with Germline and Somatic NF1 Gene Mutations
  • Dysplasia of the Orbit and Adjacent Bone Associated with Plexiform Neurofibroma and Ocular Disease in 42 NF-1 Patients
  • A patient with loss of vision in the right eye and neurofibromatosis type 1
  • Radiological classification of optic pathway gliomas: experience of a modified functional classification system
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