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Research ArticleSpine Imaging and Spine Image-Guided Interventions

Potential Value of Vertebral Proton MR Spectroscopy in Determining Bone Weakness

Dieter Schellinger, Chin Shoou Lin, Hatice Gul Hatipoglu and Djamil Fertikh
American Journal of Neuroradiology September 2001, 22 (8) 1620-1627;
Dieter Schellinger
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Chin Shoou Lin
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Hatice Gul Hatipoglu
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Djamil Fertikh
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    fig 1.

    Relationship of age, sex, and percent fat fraction (%FF). Patients are grouped by decades of age; within each decade group, male and female subjects are separately represented. There is a linear increase of %FF with age and a difference in this variable between male and female subjects.fig 2. %FF for both normal and abnormal bone, by decades of age. Abnormal bone has a higher %FF in all age groups

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    fig 3.

    Comparison of patients with and a patient without Schmorl's nodes, the most common pathologic finding.

    A, Schmorl's nodes at the lower thoracic and lumbar levels in a 38-year-old man. The 1H MRS shows a water peak (left) and a lipid peak (right). The LWR is 1.1, which yields a %FF of 52. This is relatively high for this age group (see fig 2).

    B, Schmorl's nodes at the inferior endplates of L2 and L3 in a 60-year-old man. The 1H MRS shows the lipid peak (right) to be much higher than the water peak (left). The LWR measured 1.76, which yields a %FF of 64. This is relatively high for this age group (see fig 2).

    C, Normal bone in a 17-year-old girl. The LWR measured 0.19, which yields a %FF of 16.

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    fig 4.

    Examples of compression fractures.

    A, An 87-year-old man with recent compression fracture of L3 and Schmorl's node at the superior endplate of L2. The 1H MRS at L2 revealed a LWR of 2.3, for a %FF of 70, which is relatively high for this age group.

    B, An 80-year-old woman with recent compression fracture of L1, probable fracture at the inferior L3 vertebral body, and inferior endplate depression at L4 and L5. The 1H MRS at L2 shows a very prominent lipid peak. The LWR measured 2.4, for a %FF of 71, which is relatively high for this age group.

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    TABLE 1:

    Summary of results by decades of age*

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    TABLE 2:

    Summary of results, control and abnormal subjects

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American Journal of Neuroradiology: 22 (8)
American Journal of Neuroradiology
Vol. 22, Issue 8
1 Sep 2001
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Cite this article
Dieter Schellinger, Chin Shoou Lin, Hatice Gul Hatipoglu, Djamil Fertikh
Potential Value of Vertebral Proton MR Spectroscopy in Determining Bone Weakness
American Journal of Neuroradiology Sep 2001, 22 (8) 1620-1627;

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Potential Value of Vertebral Proton MR Spectroscopy in Determining Bone Weakness
Dieter Schellinger, Chin Shoou Lin, Hatice Gul Hatipoglu, Djamil Fertikh
American Journal of Neuroradiology Sep 2001, 22 (8) 1620-1627;
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