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Tables
- TABLE 1:
Clinical, laboratory, and MR imaging findings in patients with ADEM at presentation
Patient No./Age(y)/Sex Main Clinical Features Clinical Outcome MR Imaging Findings at Presentation MR Imaging Findings at ≥6 Mo CSF Findings 1/47/M Confusion, left hemiparesis Complete recovery Multiple brain WM lesions Complete resolution of lesions Not obtained 2/22/M Tetraparesis, urine retention Complete recovery Multiple brain and spinal cord WM lesions, one hyperintense lesion in the left thalamus Marked but incomplete resolution of brain lesions, complete resolution of cord lesions Cells increased, OB 3/21/F Drowsiness, right hemiparesis Complete recovery Multiple brain WM lesions, one hyperintense lesion in the left basal ganglia Incomplete resolution of lesions Cells and protein level increased 4/37/F Confusion, left hemiparesis Almost complete recovery Multiple brain WM lesions Incomplete resolution of lesions Cells increased 5/31/F Drowsiness, right hemiparesis Complete recovery Multiple brain WM lesions Complete resolution of lesions Normal 6/40/F Paraparesis, urine retention Complete recovery Multiple brain and spinal cord WM lesions Marked but incomplete resolution of brain and cord lesions Cells and protein level increase, OB 7/22/M Drowsiness, diplopia, tetraparesis, ataxia Complete recovery Multiple brain WM lesions Incomplete resolution of lesions Protein level increased 8/51/M Ataxia, paraparesis Marked improvement Multiple brain and spinal cord WM lesions Incomplete resolution of brain and cord lesions Protein level increased, OB Note.—OB indicates oligoclonal bands; WM, white matter.
Finding Patients with ADEM Patients with MS Lesion volume on T2-weighted image (mL) 2.5 (0.0–16.4) 5.1 (0.4–16.0) Lesion MTR (%) 38.2 (31.5–43.2) 37.2 (31.5–40.6) Lesion D̅ (× 10−3 mm2/s) 0.97 (0.82–1.30) 0.93 (0.82–1.03) Note.—Data are the means; data in parentheses are the ranges.
- TABLE 3:
MTR and D̅ histogram metrics in NABT in healthy volunteers, patients with ADEM, and patients with MS
Finding Control Subjects Patients with ADEM Patients with MS P Value Patients with ADEM vs Patients with MS Control Subjects vs Patients with MS MTR (%) 40.6 (1.4) 41.3 (1.24) 38.6 (1.08) <.001 .003 MTR peak height 117.7 (13.0) 105.6 (19.2) 104.4 (14.3) >.05 .05 MTR peak position (%) 35.7 (1.7) 36.8 (1.5) 33.2 (1.7) <.001 .007 D̅ (× 10−3 mm2/s) 0.93 (0.05) 0.92 (0.03) 0.98 (0.06) .03 .009 D̅ peak height 110.7 (12.5) 97.3 (19.0) 89.9 (11.0) >.05 <.001 D̅ peak position (× 10−3 mm2/s) 0.77 (0.04) 0.75 (0.02) 0.77 (0.04) >.05 >.05 Note.—Data are the means; data in parentheses are the SDs. No significant difference between control subjects and patients with ADEM was found.
- TABLE 4:
MTR histogram metrics in cervical cord tissue in healthy volunteers, patients with ADEM, and patients with MS
Finding Control Subjects Patients with ADEM Patients with MS P Value Patients with ADEM vs Patients with MS Control Subjects vs Patients with MS MTR (%) 45.7 (2.3) 43.7 (2.5) 39.2 (3.2) .005 <.001 MTR peak height 69.6 (27.7) 67.8 (10.3) 65.4 (14.9) >.05 >.05 MTR peak position (%) 40.8 (2.3) 39.0 (4.0) 34.3 (2.6) .008 <.001 Note.—Data are the means; data in parentheses are the SDs. No significant difference between control subjects and patients with ADEM was found.
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