Research ArticleBRAIN
Sandlike Appearance of Virchow-Robin Spaces in Early Multiple Sclerosis: A Novel Neuroradiologic Marker
Anat Achiron and Meir Faibel
American Journal of Neuroradiology March 2002, 23 (3) 376-380;

References
- ↵Hutchings M, Weller RO. Anatomical relationships of the pia mater to cerebral blood vessels in man. J Neurosurg 1986;65:316–325
- ↵Zhang ET, Inman CB, Weller RO. Interrelationships of the pia mater and the perivascular (Virchow-Robin) spaces in the human cerebrum. J Anat 1990;170:111–123
- ↵Jungreis CA, Kanal E, Hirsch WL, et al. Normal perivascular spaces mimicking lacunar infarction: MR imaging. Radiology 1988;169:101–104
- ↵Heier LA, Bauer CJ, Schwartz L, Zimmerman RD, Morgello S, Deck MD. Large Virchow-Robin spaces: MR-clinical correlation. AJNR Am J Neuroradiol 1989;10:929–936
- ↵Bokura H, Kobayashi S, Yamaguchi S. Distinguishing silent lacunar infarction from enlarged Virchow-Robin spaces: a magnetic resonance imaging and pathological study. J Neurol 1998;245:116–122
- ↵Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983;13:227–231
- ↵Fazekas F, Barkhof F, Filippi M, et al. The contribution of magnetic resonance imaging to the diagnosis of multiple sclerosis. Neurology 1999;53:448–456
- ↵Braffman BH, Zimmerman RA, Trojanowski JQ, Gonatas NK, Hickey WF, Schlaepfer WW. Brain MR: pathologic correlation with gross and histopathology, I: lacunar infarction and Virchow-Robin spaces. AJR Am J Roentgenol 1988;151:551–558
- ↵Filippi M, Horsfield MA, Bressi S, et al. Intra- and inter-observer agreement of brain MRI lesion volume measurements in multiple sclerosis: a comparison of techniques. Brain 1995;118:1593–1600
- ↵Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986;1:307–310
- ↵
- ↵Matsumoto Y, Fujiwara M. The immunopathology of adoptively transferred experimental allergic encephalomyelitis (EAE) in Lewis rats, I: immunohistochemical examination of developing lesions of EAE. J Neurol Sci 1987;77:35–47
- ↵Becker NH, Novikoff AB, Zimmerman HM. Fine structure observations of the uptake of intravenously injected peroxidase by the rat choroid plexus. J Histochem Cytochem 1967;15:160–165
- ↵
- ↵Broadwell RD, Sofroniew MV. Serum proteins bypass the blood-brain fluid barriers for extracellular entry to the central nervous system. Exp Neurol 1993;120:245–263
- ↵Prineas J. Pathology of the early lesion in multiple sclerosis. Hum Pathol 1975;6:531–554
- ↵Tourtellotte WW, Ma BI. Multiple sclerosis: the blood-brain-barrier and the measurement of de novo central nervous system IgG synthesis. Neurology 1978;28:76–83
- ↵Compston A, Scolding N, Wren D, Noble M. The pathogenesis of demyelinating disease: insights from cell biology. Trends Neurosci 1991;14:175–182
- ↵
- ↵Raine CS, Snyder DH, Valsamis MP, Stone SH. Chronic experimental allergic encephalomyelitis in inbred guinea pigs: an ultrastructural study. Lab Invest 1974;31:369–380
- ↵
- ↵Mirfakhraee M, Crofford MJ, Guinto FC, Nauta HJ, Weedn VW. Virchow-Robin space: a path of spread in neurosarcoidosis. Radiology 1986;158:715–720
- ↵Miszkiel KA, Hall-Craggs MA, Miller RF, Kendall BE, Wilkinson ID, Paley MN, Harrison MJ. The spectrum of MRI findings in CNS cryptococcosis in AIDS. Clin Radiol 1996;51:842–850
- ↵Lee SC, Dickson DW, Casadevall A. Pathology of cryptococcal meningoencephalitis: analysis of 27 patients with pathogenetic implications. Hum Pathol 1996;27:839–847
- ↵Fisher CM. Lacunar strokes and infarcts: a review. Neurology 1982;32:871–876
- ↵Murata R, Nakajima S, Tanaka A, et al. MR imaging of the brain in patients with mucopolysaccharidosis. AJNR Am J Neuroradiol 1989;10:1165–1170
- ↵
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Anat Achiron, Meir Faibel
Sandlike Appearance of Virchow-Robin Spaces in Early Multiple Sclerosis: A Novel Neuroradiologic Marker
American Journal of Neuroradiology Mar 2002, 23 (3) 376-380;
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