Article Figures & Data
Figures
- Fig 1.
MR images of two patients with ICH show the presence of a hyperintense halo on T2-weighted MR images (T2 MRI) and elevated ADC values in corresponding brain regions on diffusion-weighted images. Both characteristics are compatible with elevated interstitial tissue water content, suggestive of vasogenic brain edema. The diffusion-weighted images show regions of interest in the perihematoma tissue and in the contralateral hemisphere that were chosen for ADC analysis.
- Fig 2.
Significant correlation between blood clot volume and ADC in the perihematoma tissue surrounding edema in nine patients with ICH (Pearson correlation coefficient 0.7, P=.04).
- Fig 3.
Significant correlation between blood clot volume and ADC in corresponding homologous brain regions contralateral to the high T2 signal intensity perihematoma halo used as surrogate of vasogenic brain edema in nine patients with ICH (Pearson correlation coefficient 0.8, P=.02).
Tables
Clinical and radiologic features of patient cohort
Patient (No.) Age (y)/ Sex MAP (mm Hg) Time to MR Imaging (days) Cause of ICH Location Hematoma Volume (cc) on T2-weighted MR Images ADC in Perihematoma Edema (×10−5 mm2/s) ADC in Contralateral Hemisphere (×10−5 mm2/s) 1 62/M 120 2 HTN L thalamus + IVH 2.6 120.1 ± 22.6 92.7 ± 21 2 72 /M 95 2 HTN L basal ganglia 6.5 131.7 ± 1.9 76.5 ± 1.3 3 44/F 85 3 Probable AVM R temporal lobe 32 137.2 ± 16.5 86.2 ± 7 4 87 /F 105 4 HTN L basal ganglia 37 162.0 ± 14.9 88.9 ± 4.2 5 52/F 130 2 HTN L basal ganglia 26 223.1 ± 42.1 84.9 ± 6.7 6 70 /M 95 6 HTN L basal ganglia 74 302.5 ± 46.5 102.1 ± 8.7 7 36/M 90 2 Cocaine induced R parietal + IVH 39 194.7 ± 51.9 86.7 ± 11.9 8 61 /M 110 1 HTN L basal ganglia 4.4 140.8 ± 12.8 77.7 ± 0.4 9 87/F 90 9 Probable AA L basal ganglia + IVH 56 140.6 ± 14.8 92.5 ± 14.2 Note.—MAP indicates mean arterial pressure; ICH, intracerebral hemorrhage; ADC, apparent diffusion coefficient; M, male; F, female; HTN, hypertension; AVM, arteriovenous malformation; AA, amyloid angiopathy; IVH, intraventricular hemorrhage.
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