Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Other Publications
    • ajnr

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.


AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

Research ArticleBRAIN

Role of the Corpus Callosum in Functional Connectivity

Michelle Quigley, Dietmar Cordes, Pat Turski, Chad Moritz, Victor Haughton, Raj Seth and M. Elizabeth Meyerand
American Journal of Neuroradiology February 2003, 24 (2) 208-212;
Michelle Quigley
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Dietmar Cordes
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Pat Turski
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Chad Moritz
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Victor Haughton
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Raj Seth
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Elizabeth Meyerand
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

Article Figures & Data

Figures

  • Tables
  • Fig 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 1.

    Functional connectivity and activation in the sensorimotor cortex of the three patients with agenesis of the corpus callosum. Left, Image displays the activation data from sensorimotor cortex identified by bilateral finger tapping. Middle, Image displays the functional connectivity data as the voxels functionally connected with a seed voxel cluster were chosen in the right sensorimotor cortex. Right, Image displays the functional connectivity data as voxels functionally connected to a seed voxel were selected in the left sensorimotor cortex. Note that with one exception (middle image in C), all functionally connected voxels are in the hemisphere ipsilateral to that of the seed voxel.

    A, Patient A.

    B, Patient B.

    C, Patient C.

  • Fig 2.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 2.

    Functional connectivity in the auditory cortex of the three patients with agenesis of the corpus callosum. Left, Image displays the activation data from the auditory cortex during a text-listening task. Middle, Image displays the functional connectivity data as the voxels functionally connected to a seed voxel cluster were chosen in the right auditory cortex. Right, Image displays the functional connectivity data as voxels functionally connected to a seed voxel were selected in the left auditory cortex.

    A, Patient A.

    B, Patient B.

    C, Patient C

  • Fig 3.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 3.

    Functional connectivity maps from healthy control subjects with an intact corpus callosum. Notice the bilateral connectivity in both maps in contrast to the agenesis data shown in Figures 1 and 2.

    A, Seed voxel chosen from the right auditory cortex.

    B, Seed voxel chosen from the right sensorimotor cortex.

Tables

  • Figures
    • View popup
    TABLE:

    Number of Functionally Connected Voxels in Each Hemisphere for a Seed Voxel in One Hemisphere in the Sensorimotor or Auditory Cortex

    A: Pattern of functionally connected voxels in sensorimotor cortex
    Patient and Seed Voxel ClusterSeed Voxel in L HemisphereSeed Voxel in R Hemisphere
    No. of Voxels in the LHNo. of Voxels in the RHNo. of Voxels in the LHNo. of Voxels in the RH
    A
     15006
     260NANA
     380NANA
     4100NANA
    B
     170012
     280014
     36006
     4100717
     5197NANA
    C
     18025
     27002
    B: Pattern of functionally connected voxels in auditory cortex
    Patient and Seed Voxel ClusterSeed Voxel in L HemisphereSeed Voxel in R Hemisphere
    No. of Voxels in the LHNo. of Voxels in the RHNo. of Voxels in the LHNo. of Voxels in the RH
    A, 16003
    B
     16009
    27005
     35007
     490010
     5NANA09
    C, 15003
    • Note.—The seed voxels were correlated with every other voxel in the data set, and voxels exceeding a threshold of 0.4 (P < .01) were classified as functionally connected. LH indicates the left hemisphere; RH, right hemisphere; NA, not applicable (three patients had different number of clusters in each hemisphere).

Back to top

In this issue

American Journal of Neuroradiology: 24 (2)
American Journal of Neuroradiology
Vol. 24, Issue 2
1 Feb 2003
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Role of the Corpus Callosum in Functional Connectivity
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
Michelle Quigley, Dietmar Cordes, Pat Turski, Chad Moritz, Victor Haughton, Raj Seth, M. Elizabeth Meyerand
Role of the Corpus Callosum in Functional Connectivity
American Journal of Neuroradiology Feb 2003, 24 (2) 208-212;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Role of the Corpus Callosum in Functional Connectivity
Michelle Quigley, Dietmar Cordes, Pat Turski, Chad Moritz, Victor Haughton, Raj Seth, M. Elizabeth Meyerand
American Journal of Neuroradiology Feb 2003, 24 (2) 208-212;
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Callosal Interhemispheric Communication in Mild Traumatic Brain Injury: A Mediation Analysis on WM Microstructure Effects
  • Laminar-specific interhemispheric connectivity mapping with bilateral line-scanning fMRI
  • Increased cognitive complexity reveals abnormal brain network activity in individuals with corpus callosum dysgenesis
  • On the role of the corpus callosum in interhemispheric functional connectivity in humans
  • Stable long-range interhemispheric coordination is supported by direct anatomical projections
  • Causal effect of disconnection lesions on interhemispheric functional connectivity in rhesus monkeys
  • Interhemispheric Functional Connectivity following Prenatal or Perinatal Brain Injury Predicts Receptive Language Outcome
  • Impaired interhemispheric connectivity in medication-naive patients with major depressive disorder
  • Intact Bilateral Resting-State Networks in the Absence of the Corpus Callosum
  • Predicting human resting-state functional connectivity from structural connectivity
  • Regional Variation in Interhemispheric Coordination of Intrinsic Hemodynamic Fluctuations
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Optimal MRI Sequence for Identifying Occlusion Location in Acute Stroke: Which Value of Time-Resolved Contrast-Enhanced MRA?
  • SWI or T2*: Which MRI Sequence to Use in the Detection of Cerebral Microbleeds? The Karolinska Imaging Dementia Study
  • Progression of Microstructural Damage in Spinocerebellar Ataxia Type 2: A Longitudinal DTI Study
Show more Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editors Choice
  • Fellow Journal Club
  • Letters to the Editor

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • Special Collections

Resources

  • News and Updates
  • Turn around Times
  • Submit a Manuscript
  • Author Policies
  • Manuscript Submission Guidelines
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Submit a Case
  • Become a Reviewer/Academy of Reviewers
  • Get Peer Review Credit from Publons

Multimedia

  • AJNR Podcast
  • AJNR SCANtastic
  • Video Articles

About Us

  • About AJNR
  • Editorial Board
  • Not an AJNR Subscriber? Join Now
  • Alerts
  • Feedback
  • Advertise with us
  • Librarian Resources
  • Permissions
  • Terms and Conditions

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire