Research ArticleBRAIN
Reliable Callosal Measurement: Population Normative Data Confirm Sex-Related Differences
Tejal N. Mitchell, Samantha L. Free, Martin Merschhemke, Louis Lemieux, Sanjay M. Sisodiya and Simon D. Shorvon
American Journal of Neuroradiology March 2003, 24 (3) 410-418;
Tejal N. Mitchell
Samantha L. Free
Martin Merschhemke
Louis Lemieux
Sanjay M. Sisodiya

References
- ↵Tramo MJ, Baynes K, Fendrich R, et al. Hemispheric specialisation and interhemispheric integration: insights from experiments with commissurotomy patients. In: Reeves AG, Roberts D W, eds. Epilepsy and the Corpus Callosum II. New York: Plenum Press;1995 :263–295
- Lausberg H, Gottert R, Munssinger U, Boegner F, Marx P. Callosal disconnection syndrome in a left-handed patient due to infarction of the total length of the corpus callosum. Neuropsychologia 1999;37:253–265
- Forster B, Corballis MC. Interhemispheric transfer of colour and shape information in the presence and absence of the corpus callosum. Neuropsychologia 2000;38:32–45
- ↵Funnell MG, Corballis PM, Gazzaniga MS. Cortical and subcortical interhemispheric interactions following partial and complete callosotomy. Arch Neurol 2000;57:185–189
- ↵Tomasch J. Size, distribution, and number of fibres in the human corpus callosum. Anatomical Records 1954;119:119–135
- Aboitiz F, Scheibel AB, Fisher RS, Zaidel E. Individual differences in brain asymmetries and fiber composition in the human corpus callosum. Brain Res 1992;598:154–161
- ↵Evangelou N, Esiri MM, Smith S, Palace J, Matthews PM. Quantitative pathological evidence for axonal loss in normal appearing white matter in multiple sclerosis. Ann Neurol 2000;47:391–395
- ↵Aboitiz F. Fiber composition of the human corpus callosum. Brain Research 1992;598:143–153
- ↵Witelson SF. Hand and sex differences in the isthmus and genu of the human corpus callosum. A postmortem morphological study. Brain 1989;112:799–835
- ↵Aboitiz F, Scheibel AB, Zaidel E. Morphometry of the Sylvian fissure and the corpus callosum, with emphasis on sex differences. Brain 1992;115:1521–1541
- ↵Habib M, Gayraud D, Oliva A, Regis J, Salamon G, Khalil R. Effects of handedness and sex on the morphology of the corpus callosum: a study with brain magnetic resonance imaging. Brain Cogn 1991;16:41–61
- ↵Davatzikos C, Resnick SM. Sex differences in anatomic measures of interhemispheric connectivity: correlations with cognition in women but not men. Cereb Cortex 1998;8:635–640
- ↵Moffat SD, Hampson E, Lee DH. Morphology of the planum temporale and corpus callosum in left handers with evidence of left and right hemisphere speech representation. Brain 1998;121:2369–2379
- ↵Doraiswamy PM, Figiel GS, Husain MM, et al. Aging of the human corpus callosum: magnetic resonance imaging in normal volunteers. J Neuropsychiatry Clin Neurosci 1991;3:392–397
- ↵Parashos IA, Wilkinson WE, Coffey CE. Magnetic resonance imaging of the corpus callosum: predictors of size in normal adults. J Neuropsychiatry Clin Neurosci 1995;7:35–41
- ↵Laissy JP, Patrux B, Duchateau C, et al. Midsagittal MR measurements of the corpus callosum in healthy subjects and diseased patients: a prospective survey. AJNR Am J Neuroradiol 1993;14:145–154
- ↵Narr KL, Thompson PM, Sharma T, Moussai J, Cannestra AF, Toga AW. Mapping morphology of the corpus callosum in schizophrenia. Cereb Cortex 2000;10:40–49
- ↵Hynd GW, Hall J, Novey ES, et al. Dyslexia and corpus callosum morphology. Arch Neurol 1995;52:32–38
- ↵Pelletier J, Habib M, Lyon CO, Salamon G, Poncet M, Khalil R. Functional and magnetic resonance imaging correlates of callosal involvement in multiple sclerosis. Arch Neurol 1993;50:1077–1082
- Simon JH, Jacobs LD, Campion MK, et al. A longitudinal study of brain atrophy in relapsing multiple sclerosis: The Multiple Sclerosis Collaborative Research Group (MSCRG). Neurology 1999;53:139–148
- ↵Evangelou N, Konz D, Esiri MM, Smith S, Palace J, Matthews PM. Regional axonal loss in the corpus callosum correlates with cerebral white matter lesion volume and distribution in multiple sclerosis. Brain 2000;123:1845–1849
- ↵Hampel H, Teipel SJ, Alexander GE, et al. Corpus callosum atrophy is a possible indicator of region- and cell type-specific neuronal degeneration in Alzheimer disease: a magnetic resonance imaging analysis. Arch Neurol 1998;55:193–198
- ↵Pantel J, Schroder J, Jauss M, et al. Topography of callosal atrophy reflects distribution of regional cerebral volume reduction in Alzheimer’s disease. Psychiatry Res 1999;90:181–192
- ↵
- ↵Rauch RA, Jinkins JR. Variability of corpus callosal area measurements from midsagittal MR images: effect of subject placement within the scanner. AJNR Am J Neuroradiol 1996;17:27–28
- ↵Moffat SD, Hampson E, Wickett JC, Vernon PA, Lee DH. Testosterone is correlated with regional morphology of the human corpus callosum. Brain Res 1997;767:297–304
- Thompson PM, Moussai J, Zohoori S, et al. Cortical variability and asymmetry in normal aging and Alzheimer’s disease. Cereb Cortex 1998;8:492–509
- ↵Jäncke L, Preis S, Steinmetz H. The relation between forebrain volume and midsagittal size of the corpus callosum in children. Neuroreport 1999;10:2981–2985
- ↵Chapman LJ, Chapman JP. The measurement of handedness. Brain Cogn 1987;6:175–183
- ↵Liu RS, Lemieux L, Bell GS, et al. A longitudinal quantitative MRI study of community-based patients with chronic epilepsy and newly diagnosed seizures: methodology and preliminary findings. Neuroimage 2001;14:231–243
- ↵Lemieux L, Liu RSN, Duncan JS. Hippocampal and cerebellar volumetry in serially acquired MRI volume scans. Magn Reson Imaging 2000;18:1027–1033
- ↵Moran NF, Lemieux L, Maudgil D, Kitchen ND, Fish DR, Shorvon SD. Analysis of temporal lobe resections in MR images. Epilepsia 1999;40:1077–1084
- ↵Sisodiya SM, Free SL, Stevens JM, Fish DR, Shorvon SD. Widespread cerebral structural changes in patients with cortical dysgenesis and epilepsy. Brain 1995;118:1039–1050
- ↵Ashburner J, Friston KJ. Voxel-based morphometry-the methods. Neuroimage 2000;11:805–821
- ↵Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986;1:307–310
- ↵Jäncke L, Staiger JF, Schlaug G, Huang Y, Steinmetz H. The relationship between corpus callosum size and forebrain volume. Cereb Cortex 1997;7:48–56
- ↵Peters M, Jäncke L, Zilles K. Comparison of overall brain volume and midsagittal corpus callosum surface area as obtained from NMR scans and direct anatomical measures: a within-subject study on autopsy brains. Neuropsychologia 2000;38:1375–1381
- ↵Thompson PM, Moussai J, Zohoori S, et al. Cortical variability and asymmetry in normal aging and Alzheimer’s disease. Cereb Cortex 1998;8:492–509
- ↵Davatzikos C, Resnick SM. Sex differences in anatomic measures of interhemispheric connectivity: correlations with cognition in women but not men. Cereb Cortex 1998;8:635–640
- ↵Oka S, Miyamoto O, Janjua NA, et al. Re-evaluation of sexual dimorphism in human corpus callosum. Neuroreport 1999;10:937–940
- ↵Doraiswamy PM, Figiel GS, Husain MM, et al. Aging of the human corpus callosum: magnetic resonance imaging in normal volunteers. J Neuropsychiatry Clin Neurosci 1991;3:392–397
- Laissy JP, Patrux B, Duchateau C, et al. Midsagittal MR measurements of the corpus callosum in healthy subjects and diseased patients: a prospective survey. AJNR Am J Neuroradiol 1993;14:145–154
- ↵Parashos IA, Wilkinson WE, Coffey CE. Magnetic resonance imaging of the corpus callosum: predictors of size in normal adults. J Neuropsychiatry Clin Neurosci 1995;7:35–41
- ↵Habib M, Gayraud D, Oliva A, Regis J, Salamon G, Khalil R. Effects of handedness and sex on the morphology of the corpus callosum: a study with brain magnetic resonance imaging. Brain Cogn 1991;16:41–61
- ↵Jäncke L, Preis S, Steinmetz H. The relation between forebrain volume and midsagittal size of the corpus callosum in children. Neuroreport 1999;10:2981–2985
- ↵Nopoulos P, Flaum M, O’Leary D, Andreasen NC. Sexual dimorphism in the human brain: evaluation of tissue volume, tissue composition and surface anatomy using magnetic resonance imaging. Psychiatry Res 2000;98:1–13
- ↵Goldstein JM, Seidman LJ, Horton NJ, et al. Normal sexual dimorphism of the adult human brain assessed by in vivo magnetic resonance imaging. Cereb Cortex 2001;11:490–497
- ↵Kulynych JJ, Vladar K, Jones DW, Weinberger DR. Gender differences in the normal lateralization of the supratemporal cortex: MRI surface-rendering morphometry of Heschl’s gyrus and the planum temporale. Cereb Cortex 1994;4:107–118
- Amunts K, Jäncke L, Mohlberg H, Steinmetz H, Zilles K. Interhemispheric asymmetry of the human motor cortex related to handedness and gender. Neuropsychologia 2000;38:304–312
- ↵Good CD, Johnsrude I, Ashburner J, Henson RN, Friston KJ, Frackowiak RS. Cerebral asymmetry and the effects of sex and handedness on brain structure: a voxel-based morphometric analysis of 465 normal adult human brains. Neuroimage 2001;14:685–700
- ↵Shaywitz BA, Shaywitz SE, Pugh KR, et al. Sex differences in the functional organization of the brain for language. Nature 1995;373:607–609
- ↵Gur RC, Turetsky BI, Matsui M, et al. Sex differences in brain gray and white matter in healthy young adults: correlations with cognitive performance. J Neurosci 1999;19:4065–4072
- ↵Bermudez P, Zatorre RJ. Sexual dimorphism in the corpus callosum: methodological considerations in MRI morphometry. Neuroimage 2001;13:1121–1130
- ↵Collins DL, Neelin P, Peters TM, Evans AC. Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space. J Comput Assist Tomogr 1994;18:192–205
- ↵
- ↵Innocenti GM. General organisation of callosal connections in the cerebral cortex. In: Jones EG, Peters A, eds. Cerebral Cortex. New York: Plenum Press;1986 :291–354
- ↵Barkovich AJ, Norman D. Anomalies of the corpus callosum: correlation with further anomalies of the brain. AJR Am J Roentgenol 1988;151:171–179
- ↵
- ↵Leventer RJ, Phelan EM, Coleman LT, Kean MJ, Jackson GD, Harvey AS. Clinical and imaging features of cortical malformations in childhood. Neurology 1999;53:715–722
- ↵Sisodiya SM, Free SL. Disproportion of cerebral surface areas and volumes in cerebral dysgenesis. MRI-based evidence for connectional abnormalities. Brain 1997;120:271–281
- ↵Hayashi M, Sakamoto K, Kurata K, Nagata J, Satoh J, Morimatsu Y. Septo-optic dysplasia with cerebellar hypoplasia in Cornelia de Lange syndrome. Acta Neuropathol Berl 1996;92:625–630
- ↵Meyer BU, Roricht S, Niehaus L. Morphology of acallosal brains as assessed by MRI in six patients leading a normal daily life. J Neurol 1998;245:106–110
- ↵Giannetti S, Gaglini P, Granato A, Di Rocco C. Organization of callosal connections in rats with experimentally induced microgyria. Childs Nerv Syst 1999;15:444–448
- ↵Toran-Allerand CD, Singh M, Setalo G. Novel mechanisms of estrogen action in the brain: new players in an old story. Front Neuroendocrinol 1999;20:97–121
- ↵
- ↵Fox JW, Lamperti ED, Eksioglu YZ, et al. Mutations in filamin 1 prevent migration of cerebral cortical neurons in human periventricular heterotopia. Neuron 1998;21:1315–1325
- ↵des P, V, Francis F, Pinard JM, et al. doublecortin is the major gene causing X-linked subcortical laminar heterotopia (SCLH). Hum Mol Genet 1998;7:1063–1070
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Tejal N. Mitchell, Samantha L. Free, Martin Merschhemke, Louis Lemieux, Sanjay M. Sisodiya, Simon D. Shorvon
Reliable Callosal Measurement: Population Normative Data Confirm Sex-Related Differences
American Journal of Neuroradiology Mar 2003, 24 (3) 410-418;
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