Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Other Publications
    • ajnr

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.


AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

Getting new auth cookie, if you see this message a lot, tell someone!
Research ArticleBRAIN

Reliable Callosal Measurement: Population Normative Data Confirm Sex-Related Differences

Tejal N. Mitchell, Samantha L. Free, Martin Merschhemke, Louis Lemieux, Sanjay M. Sisodiya and Simon D. Shorvon
American Journal of Neuroradiology March 2003, 24 (3) 410-418;
Tejal N. Mitchell
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Samantha L. Free
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Martin Merschhemke
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Louis Lemieux
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sanjay M. Sisodiya
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Simon D. Shorvon
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. ↵
    Tramo MJ, Baynes K, Fendrich R, et al. Hemispheric specialisation and interhemispheric integration: insights from experiments with commissurotomy patients. In: Reeves AG, Roberts D W, eds. Epilepsy and the Corpus Callosum II. New York: Plenum Press;1995 :263–295
  2. Lausberg H, Gottert R, Munssinger U, Boegner F, Marx P. Callosal disconnection syndrome in a left-handed patient due to infarction of the total length of the corpus callosum. Neuropsychologia 1999;37:253–265
    CrossRefPubMedWeb of Science
  3. Finger S, Kanne SM. The discovery and rediscovery of the role of the corpus callosum. Brain Res Bull 1999;50:419–420
    CrossRefPubMed
  4. Forster B, Corballis MC. Interhemispheric transfer of colour and shape information in the presence and absence of the corpus callosum. Neuropsychologia 2000;38:32–45
    CrossRefPubMedWeb of Science
  5. ↵
    Funnell MG, Corballis PM, Gazzaniga MS. Cortical and subcortical interhemispheric interactions following partial and complete callosotomy. Arch Neurol 2000;57:185–189
    CrossRefPubMedWeb of Science
  6. ↵
    Tomasch J. Size, distribution, and number of fibres in the human corpus callosum. Anatomical Records 1954;119:119–135
    CrossRef
  7. Aboitiz F, Scheibel AB, Fisher RS, Zaidel E. Individual differences in brain asymmetries and fiber composition in the human corpus callosum. Brain Res 1992;598:154–161
    CrossRefPubMedWeb of Science
  8. ↵
    Evangelou N, Esiri MM, Smith S, Palace J, Matthews PM. Quantitative pathological evidence for axonal loss in normal appearing white matter in multiple sclerosis. Ann Neurol 2000;47:391–395
    CrossRefPubMedWeb of Science
  9. ↵
    Aboitiz F. Fiber composition of the human corpus callosum. Brain Research 1992;598:143–153
    CrossRefPubMedWeb of Science
  10. ↵
    Witelson SF. Hand and sex differences in the isthmus and genu of the human corpus callosum. A postmortem morphological study. Brain 1989;112:799–835
    Abstract/FREE Full Text
  11. ↵
    Aboitiz F, Scheibel AB, Zaidel E. Morphometry of the Sylvian fissure and the corpus callosum, with emphasis on sex differences. Brain 1992;115:1521–1541
    Abstract/FREE Full Text
  12. ↵
    Habib M, Gayraud D, Oliva A, Regis J, Salamon G, Khalil R. Effects of handedness and sex on the morphology of the corpus callosum: a study with brain magnetic resonance imaging. Brain Cogn 1991;16:41–61
    CrossRefPubMedWeb of Science
  13. ↵
    Davatzikos C, Resnick SM. Sex differences in anatomic measures of interhemispheric connectivity: correlations with cognition in women but not men. Cereb Cortex 1998;8:635–640
    Abstract/FREE Full Text
  14. ↵
    Moffat SD, Hampson E, Lee DH. Morphology of the planum temporale and corpus callosum in left handers with evidence of left and right hemisphere speech representation. Brain 1998;121:2369–2379
    Abstract/FREE Full Text
  15. ↵
    Doraiswamy PM, Figiel GS, Husain MM, et al. Aging of the human corpus callosum: magnetic resonance imaging in normal volunteers. J Neuropsychiatry Clin Neurosci 1991;3:392–397
    PubMedWeb of Science
  16. ↵
    Parashos IA, Wilkinson WE, Coffey CE. Magnetic resonance imaging of the corpus callosum: predictors of size in normal adults. J Neuropsychiatry Clin Neurosci 1995;7:35–41
    PubMedWeb of Science
  17. ↵
    Laissy JP, Patrux B, Duchateau C, et al. Midsagittal MR measurements of the corpus callosum in healthy subjects and diseased patients: a prospective survey. AJNR Am J Neuroradiol 1993;14:145–154
    Abstract/FREE Full Text
  18. ↵
    Narr KL, Thompson PM, Sharma T, Moussai J, Cannestra AF, Toga AW. Mapping morphology of the corpus callosum in schizophrenia. Cereb Cortex 2000;10:40–49
    Abstract/FREE Full Text
  19. ↵
    Hynd GW, Hall J, Novey ES, et al. Dyslexia and corpus callosum morphology. Arch Neurol 1995;52:32–38
    CrossRefPubMedWeb of Science
  20. ↵
    Pelletier J, Habib M, Lyon CO, Salamon G, Poncet M, Khalil R. Functional and magnetic resonance imaging correlates of callosal involvement in multiple sclerosis. Arch Neurol 1993;50:1077–1082
    CrossRefPubMedWeb of Science
  21. Simon JH, Jacobs LD, Campion MK, et al. A longitudinal study of brain atrophy in relapsing multiple sclerosis: The Multiple Sclerosis Collaborative Research Group (MSCRG). Neurology 1999;53:139–148
    Abstract/FREE Full Text
  22. ↵
    Evangelou N, Konz D, Esiri MM, Smith S, Palace J, Matthews PM. Regional axonal loss in the corpus callosum correlates with cerebral white matter lesion volume and distribution in multiple sclerosis. Brain 2000;123:1845–1849
    Abstract/FREE Full Text
  23. ↵
    Hampel H, Teipel SJ, Alexander GE, et al. Corpus callosum atrophy is a possible indicator of region- and cell type-specific neuronal degeneration in Alzheimer disease: a magnetic resonance imaging analysis. Arch Neurol 1998;55:193–198
    CrossRefPubMedWeb of Science
  24. ↵
    Pantel J, Schroder J, Jauss M, et al. Topography of callosal atrophy reflects distribution of regional cerebral volume reduction in Alzheimer’s disease. Psychiatry Res 1999;90:181–192
    CrossRefPubMedWeb of Science
  25. ↵
    Coffman JA, Schwarzkopf SB, Olson SC, Nasrallah HA. Midsagittal cerebral anatomy by magnetic resonance imaging. The importance of slice position and thickness. Schizophr Res 1989;2:287–294
    CrossRefPubMed
  26. ↵
    Rauch RA, Jinkins JR. Variability of corpus callosal area measurements from midsagittal MR images: effect of subject placement within the scanner. AJNR Am J Neuroradiol 1996;17:27–28
    Abstract
  27. ↵
    Moffat SD, Hampson E, Wickett JC, Vernon PA, Lee DH. Testosterone is correlated with regional morphology of the human corpus callosum. Brain Res 1997;767:297–304
    CrossRefPubMedWeb of Science
  28. Thompson PM, Moussai J, Zohoori S, et al. Cortical variability and asymmetry in normal aging and Alzheimer’s disease. Cereb Cortex 1998;8:492–509
    Abstract/FREE Full Text
  29. ↵
    Jäncke L, Preis S, Steinmetz H. The relation between forebrain volume and midsagittal size of the corpus callosum in children. Neuroreport 1999;10:2981–2985
    PubMedWeb of Science
  30. ↵
    Chapman LJ, Chapman JP. The measurement of handedness. Brain Cogn 1987;6:175–183
    CrossRefPubMedWeb of Science
  31. ↵
    Liu RS, Lemieux L, Bell GS, et al. A longitudinal quantitative MRI study of community-based patients with chronic epilepsy and newly diagnosed seizures: methodology and preliminary findings. Neuroimage 2001;14:231–243
    CrossRefPubMedWeb of Science
  32. ↵
    Lemieux L, Liu RSN, Duncan JS. Hippocampal and cerebellar volumetry in serially acquired MRI volume scans. Magn Reson Imaging 2000;18:1027–1033
    CrossRefPubMedWeb of Science
  33. ↵
    Moran NF, Lemieux L, Maudgil D, Kitchen ND, Fish DR, Shorvon SD. Analysis of temporal lobe resections in MR images. Epilepsia 1999;40:1077–1084
    CrossRefPubMedWeb of Science
  34. ↵
    Sisodiya SM, Free SL, Stevens JM, Fish DR, Shorvon SD. Widespread cerebral structural changes in patients with cortical dysgenesis and epilepsy. Brain 1995;118:1039–1050
    Abstract/FREE Full Text
  35. ↵
    Ashburner J, Friston KJ. Voxel-based morphometry-the methods. Neuroimage 2000;11:805–821
    CrossRefPubMedWeb of Science
  36. ↵
    Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986;1:307–310
    CrossRefPubMedWeb of Science
  37. ↵
    Jäncke L, Staiger JF, Schlaug G, Huang Y, Steinmetz H. The relationship between corpus callosum size and forebrain volume. Cereb Cortex 1997;7:48–56
    Abstract/FREE Full Text
  38. ↵
    Peters M, Jäncke L, Zilles K. Comparison of overall brain volume and midsagittal corpus callosum surface area as obtained from NMR scans and direct anatomical measures: a within-subject study on autopsy brains. Neuropsychologia 2000;38:1375–1381
    CrossRefPubMedWeb of Science
  39. ↵
    Thompson PM, Moussai J, Zohoori S, et al. Cortical variability and asymmetry in normal aging and Alzheimer’s disease. Cereb Cortex 1998;8:492–509
  40. ↵
    Davatzikos C, Resnick SM. Sex differences in anatomic measures of interhemispheric connectivity: correlations with cognition in women but not men. Cereb Cortex 1998;8:635–640
  41. ↵
    Oka S, Miyamoto O, Janjua NA, et al. Re-evaluation of sexual dimorphism in human corpus callosum. Neuroreport 1999;10:937–940
    PubMedWeb of Science
  42. ↵
    Doraiswamy PM, Figiel GS, Husain MM, et al. Aging of the human corpus callosum: magnetic resonance imaging in normal volunteers. J Neuropsychiatry Clin Neurosci 1991;3:392–397
  43. Laissy JP, Patrux B, Duchateau C, et al. Midsagittal MR measurements of the corpus callosum in healthy subjects and diseased patients: a prospective survey. AJNR Am J Neuroradiol 1993;14:145–154
  44. ↵
    Parashos IA, Wilkinson WE, Coffey CE. Magnetic resonance imaging of the corpus callosum: predictors of size in normal adults. J Neuropsychiatry Clin Neurosci 1995;7:35–41
  45. ↵
    Habib M, Gayraud D, Oliva A, Regis J, Salamon G, Khalil R. Effects of handedness and sex on the morphology of the corpus callosum: a study with brain magnetic resonance imaging. Brain Cogn 1991;16:41–61
  46. ↵
    Jäncke L, Preis S, Steinmetz H. The relation between forebrain volume and midsagittal size of the corpus callosum in children. Neuroreport 1999;10:2981–2985
  47. ↵
    Nopoulos P, Flaum M, O’Leary D, Andreasen NC. Sexual dimorphism in the human brain: evaluation of tissue volume, tissue composition and surface anatomy using magnetic resonance imaging. Psychiatry Res 2000;98:1–13
    CrossRefPubMedWeb of Science
  48. ↵
    Goldstein JM, Seidman LJ, Horton NJ, et al. Normal sexual dimorphism of the adult human brain assessed by in vivo magnetic resonance imaging. Cereb Cortex 2001;11:490–497
    Abstract/FREE Full Text
  49. ↵
    Kulynych JJ, Vladar K, Jones DW, Weinberger DR. Gender differences in the normal lateralization of the supratemporal cortex: MRI surface-rendering morphometry of Heschl’s gyrus and the planum temporale. Cereb Cortex 1994;4:107–118
    Abstract/FREE Full Text
  50. Amunts K, Jäncke L, Mohlberg H, Steinmetz H, Zilles K. Interhemispheric asymmetry of the human motor cortex related to handedness and gender. Neuropsychologia 2000;38:304–312
    CrossRefPubMedWeb of Science
  51. ↵
    Good CD, Johnsrude I, Ashburner J, Henson RN, Friston KJ, Frackowiak RS. Cerebral asymmetry and the effects of sex and handedness on brain structure: a voxel-based morphometric analysis of 465 normal adult human brains. Neuroimage 2001;14:685–700
    CrossRefPubMedWeb of Science
  52. ↵
    Shaywitz BA, Shaywitz SE, Pugh KR, et al. Sex differences in the functional organization of the brain for language. Nature 1995;373:607–609
    CrossRefPubMedWeb of Science
  53. ↵
    Gur RC, Turetsky BI, Matsui M, et al. Sex differences in brain gray and white matter in healthy young adults: correlations with cognitive performance. J Neurosci 1999;19:4065–4072
    Abstract/FREE Full Text
  54. ↵
    Bermudez P, Zatorre RJ. Sexual dimorphism in the corpus callosum: methodological considerations in MRI morphometry. Neuroimage 2001;13:1121–1130
    PubMedWeb of Science
  55. ↵
    Collins DL, Neelin P, Peters TM, Evans AC. Automatic 3D intersubject registration of MR volumetric data in standardized Talairach space. J Comput Assist Tomogr 1994;18:192–205
    CrossRefPubMedWeb of Science
  56. ↵
    Arndt S, Rajarethinam R, Cizadlo T, O’Leary D, Downhill J, Andreasen NC. Landmark- based registration and measurement of magnetic resonance images: a reliability study. Psychiatry Res 1996;67:145–154
    CrossRefPubMed
  57. ↵
    Innocenti GM. General organisation of callosal connections in the cerebral cortex. In: Jones EG, Peters A, eds. Cerebral Cortex. New York: Plenum Press;1986 :291–354
  58. ↵
    Barkovich AJ, Norman D. Anomalies of the corpus callosum: correlation with further anomalies of the brain. AJR Am J Roentgenol 1988;151:171–179
    CrossRefPubMedWeb of Science
  59. ↵
    Billette d V, Chiron C, Robain O. Unlayered polymicrogyria and agenesis of the corpus callosum: a relevant association? Acta Neuropathol Berl 1992;83:265–270
    CrossRefPubMed
  60. ↵
    Leventer RJ, Phelan EM, Coleman LT, Kean MJ, Jackson GD, Harvey AS. Clinical and imaging features of cortical malformations in childhood. Neurology 1999;53:715–722
    Abstract/FREE Full Text
  61. ↵
    Sisodiya SM, Free SL. Disproportion of cerebral surface areas and volumes in cerebral dysgenesis. MRI-based evidence for connectional abnormalities. Brain 1997;120:271–281
    Abstract/FREE Full Text
  62. ↵
    Hayashi M, Sakamoto K, Kurata K, Nagata J, Satoh J, Morimatsu Y. Septo-optic dysplasia with cerebellar hypoplasia in Cornelia de Lange syndrome. Acta Neuropathol Berl 1996;92:625–630
    CrossRefPubMedWeb of Science
  63. ↵
    Meyer BU, Roricht S, Niehaus L. Morphology of acallosal brains as assessed by MRI in six patients leading a normal daily life. J Neurol 1998;245:106–110
    CrossRefPubMedWeb of Science
  64. ↵
    Giannetti S, Gaglini P, Granato A, Di Rocco C. Organization of callosal connections in rats with experimentally induced microgyria. Childs Nerv Syst 1999;15:444–448
    CrossRefPubMedWeb of Science
  65. ↵
    Toran-Allerand CD, Singh M, Setalo G. Novel mechanisms of estrogen action in the brain: new players in an old story. Front Neuroendocrinol 1999;20:97–121
    CrossRefPubMedWeb of Science
  66. ↵
    Beyer C. Estrogen and the developing mammalian brain. Anat Embryol Berl 1999;199:379–390
    CrossRefPubMed
  67. ↵
    Fox JW, Lamperti ED, Eksioglu YZ, et al. Mutations in filamin 1 prevent migration of cerebral cortical neurons in human periventricular heterotopia. Neuron 1998;21:1315–1325
    CrossRefPubMedWeb of Science
  68. ↵
    des P, V, Francis F, Pinard JM, et al. doublecortin is the major gene causing X-linked subcortical laminar heterotopia (SCLH). Hum Mol Genet 1998;7:1063–1070
    Abstract/FREE Full Text
Back to top

In this issue

American Journal of Neuroradiology: 24 (3)
American Journal of Neuroradiology
Vol. 24, Issue 3
1 Mar 2003
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Reliable Callosal Measurement: Population Normative Data Confirm Sex-Related Differences
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
Tejal N. Mitchell, Samantha L. Free, Martin Merschhemke, Louis Lemieux, Sanjay M. Sisodiya, Simon D. Shorvon
Reliable Callosal Measurement: Population Normative Data Confirm Sex-Related Differences
American Journal of Neuroradiology Mar 2003, 24 (3) 410-418;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Reliable Callosal Measurement: Population Normative Data Confirm Sex-Related Differences
Tejal N. Mitchell, Samantha L. Free, Martin Merschhemke, Louis Lemieux, Sanjay M. Sisodiya, Simon D. Shorvon
American Journal of Neuroradiology Mar 2003, 24 (3) 410-418;
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Conclusion
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Hand preference and the corpus callosum: Is there really no association?
  • Handedness and midsagittal corpus callosum morphology: A systematic meta-analytic evaluation
  • Regional White Matter Atrophy-Based Classification of Multiple Sclerosis in Cross-Sectional and Longitudinal Data
  • Progression of non-age-related callosal brain atrophy in multiple sclerosis: a 9-year longitudinal MRI study representing four decades of disease development
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Progression of Microstructural Damage in Spinocerebellar Ataxia Type 2: A Longitudinal DTI Study
  • Usefulness of Quantitative Susceptibility Mapping for the Diagnosis of Parkinson Disease
  • Evaluating the Effects of White Matter Multiple Sclerosis Lesions on the Volume Estimation of 6 Brain Tissue Segmentation Methods
Show more Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editors Choice
  • Fellow Journal Club
  • Letters to the Editor

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • Special Collections

Resources

  • News and Updates
  • Turn around Times
  • Submit a Manuscript
  • Author Policies
  • Manuscript Submission Guidelines
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Submit a Case
  • Become a Reviewer/Academy of Reviewers
  • Get Peer Review Credit from Publons

Multimedia

  • AJNR Podcast
  • AJNR SCANtastic
  • Video Articles

About Us

  • About AJNR
  • Editorial Board
  • Not an AJNR Subscriber? Join Now
  • Alerts
  • Feedback
  • Advertise with us
  • Librarian Resources
  • Permissions
  • Terms and Conditions

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire