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OtherBrain

CT and MR Imaging of Intracerebral Amyloidoma: Case Report and Review of the Literature

Dheeraj Gandhi, Roberto Wee and Mayank Goyal
American Journal of Neuroradiology March 2003, 24 (3) 519-522;
Dheeraj Gandhi
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Roberto Wee
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Mayank Goyal
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    Fig 1.

    CT scans obtained in 54-year-old woman with intracerebral amyloidoma.

    A, Axial non-contrast enhanced CT scan of the brain reveals a hyperattenuated comet-shaped mass in the left posterior frontal white matter. Significant vasogenic edema is also present around the mass.

    B, The mass enhances after administration of contrast material. Note the medial extension of the mass up to the lateral ventricular ependyma.

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    Fig 2.

    MR images obtained in 54-year-old woman with intracerebral amyloidoma.

    A, The mass is hypointense on this axial T1-weighted image (551/5/2 [TR/TE/NEX]).

    B, The mass is hypointense on this axial T2-weighted image (4110/110/2).

    C, The mass is hyperintense on this T1-weighted postcontrast axial image.

Tables

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  • Review of Cases of Cerebral Amyloidomas

    Author and Year*Patient (no.)/ Age (y)/SexClinical PresentationLocationNo. of LesionsCT FindingsMR Imaging FindingsAngiographic Findings
    Saltykow, 1935 (5)1/UnknownPsychiatric disturbancesCortex, WMMNANANA
    Harris and Rayport, 1979 (6)2/28/FFocal seizuresFrontal WMSHyperattenuating mass on nonenhanced scansNANA
    Spaar et al, 1981 (7)3/46/FVisual loss, headache, depressionWMMHypoattenuating lesions, enhancement on contrast-enhanced scans, extension to the lateral ventricleNAVascular displacements
    Townsend et al, 1982 (8)4/47/FCognitive declineFrontal/optic radiation, WMMHyperattenuating mass on nonenhanced scansNAAbsent venous filling in the affected region
    Townsend et al, 1982 (8)5/50/MVisual field defectsOccipital WMSHyperattenuating mass with enhancement on contrast-enhanced scansNANA
    Moreno et al, 1983 (9)6/48/MR hemianopsia, L-arm weaknessL occipital WMSRing-enhancing lesion, extension to the lateral ventricle, thickened ependymaNANormal
    Hori et al, 1988 (10)7/60/MHeadache, seizure, dementiaL frontal, cerebellum, pons (WM)MNANANA
    Cohen et al, 1992 (11)8/32/MHeadache, seizure, decreased cognitionBilateral centrum semiovale WM, 1 cortical lesionMHyperattenuating masses, contrast enhancement, extension to the lateral ventricleHypointense on T1WI, mixed intensity on T2WI, faint enhancementNA
    Eriksson et al, 1993 (2)9/76/MSeizureR parietal WM, extension to lateral ventricle and choroid plexusSNANAMass effect on the temporal horn of the lateral ventricle
    Schroder et al, 1995 (12)10/70/FAtaxia, L-leg weakness, cognitive declineR subcortical parieto-occipital, 2 smaller lesions in the ventricular wallMHyperattenuating, no edema, extension to the lateral ventricleNANormal
    Lee et al, 1995 (3)11/61/FSeizures, decreased mentationL parietal periatrial WMSHyperattenuating, partially calcified, no edemaHyperintense on T1WI, mixed intensity on T2WI, marked enhancement, no edema, extension to the lateral ventricleNA
    Caerts et al, 1997 (4)12/71/FR pyramidal syndromeL deep periventricular WMSHyperattenuating mass on nonenhanced scans, contrast enhancement, no edemaIsointense on T1WI, hyperintense on T2WI, strongly enhancing, extension to the lateral ventricleNA
    Blatter et al, 2001 (22)13/26/FR-hand paresis, dysarthriaL parieto-occipital, smaller R-sided lesionsMNAT1WI and T2WI appearance unknown, contrast enhancement, extension to the lateral ventricleNA
    Gandhi et al, 2003 (present case)14/54/FSeizuresL frontal WM, medial extension to the lateral ventricleSComet-shaped hyperattenuating mass on nonenhanced scans, contrast enhancement, medial extension up to lateral ventricle wallHypointense on T1WI and T2WI, strong contrast enhancement, surrounding edemaNA
    • Note.—L indicates left; M, multiple; NA, not applicable; R, right; S, single; T1WI, T1-weighted image; T2WI, T2-weighted image; and WM, white matter.

    • * Numbers in parentheses are reference numbers.

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American Journal of Neuroradiology: 24 (3)
American Journal of Neuroradiology
Vol. 24, Issue 3
1 Mar 2003
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Dheeraj Gandhi, Roberto Wee, Mayank Goyal
CT and MR Imaging of Intracerebral Amyloidoma: Case Report and Review of the Literature
American Journal of Neuroradiology Mar 2003, 24 (3) 519-522;

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CT and MR Imaging of Intracerebral Amyloidoma: Case Report and Review of the Literature
Dheeraj Gandhi, Roberto Wee, Mayank Goyal
American Journal of Neuroradiology Mar 2003, 24 (3) 519-522;
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