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Research ArticleINTERVENTIONAL

Influence of Geometric and Hemodynamic Parameters on Aneurysm Visualization during Three-Dimensional Rotational Angiography: An in Vitro Study

Ulrike U. Ernemann, Eckart Grönewäller, Frank B. Duffner, Oezlem Guervit, Joerg Claassen and Martin D. Skalej
American Journal of Neuroradiology April 2003, 24 (4) 597-603;
Ulrike U. Ernemann
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Eckart Grönewäller
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Frank B. Duffner
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Oezlem Guervit
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Joerg Claassen
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Martin D. Skalej
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    Fig 1.

    Aneurysm models 1–5. Arrows indicate the direction of blood flow. A indicates parent artery; B, ostium width, C, dome height; and D, dome diameter.

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    Fig 2.

    Model 2, wide-necked aneurysm in the MCA bifurcation and AcoA. Voxel size, 0.25 mm.

    A, The 5-second rotation with continuous flow shows filling defects in both aneurysms (arrows).

    B, The 8-second rotation with continuous flow shows a slight defect in the MCA aneurysm (arrow).

    C, Accurate visualization of the aneurysm is achieved in the 8-second rotation with the bolus injection.

    D, The 14-second rotation with continuous flow has higher plasticity, but it does not provide any additional information about the geometry of the aneurysm.

  • Fig 3.
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    Fig 3.

    Model 1, small-necked aneurysm in the MCA bifurcation. Voxel size, 0.13 mm.

    A, The 8-second rotation with continuous flow shows a filling defect at the medial wall of the aneurysm (arrow).

    B, The 8-second rotation with bolus injection provides accurate 3D visualization of the shape of the aneurysm.

  • Fig 4.
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    Fig 4.

    Model 3, small-necked giant lateral aneurysm. Voxel size, 0.16 mm.

    A, The true shape of the aneurysm was not visualized on the 3D reconstruction.

    B, The 14-second rotation with a bolus injection reveals only the distal aneurysmal shell.

    C, In the 14-second rotation, the proximal wall of the aneurysm is not clearly delineated, even after the administration of contrast material at a rate of 5 mL/s.

  • Fig 5.
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    Fig 5.

    Model 4, large-necked giant lateral aneurysm with large neck. Voxel size, 0.18 mm. The 8-second rotation with a bolus injection enables complete visualization of the shape of the aneurysm.

Tables

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    TABLE 1:

    Dimensions in the models of bifucation and lateral aneurysm models

    Model and Parent Artery*Ostium Width, mmDome Height, mmDome Diameter, mm
    1, MCA 3 × 34.516.510
    2, MCA 3 × 3816.510
     AcoA 2 × 261110
    3, ICA 5 × 5.582723
    4, ICA 5 × 5.5172825.5 × 24
    5, ICA 5 × 5.510.52821
     Second lobule121717
    • * AcoA indicates anterior communicating artery.

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    TABLE 2:

    Protocols used to inject the contrast material

    ProtocolDuration of Rotational Run
    5 Seconds8 Seconds14 Seconds
    Continuous flow, mL/s4.02.52.5
    Initial bolus injection, mL/s
     First phase5.0 over 2 s5.0 over 2 s4.0 over 4 s
     Second phase3.3 over 3 s1.7 over 6 s1.9 over 10 s
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American Journal of Neuroradiology: 24 (4)
American Journal of Neuroradiology
Vol. 24, Issue 4
1 Apr 2003
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Cite this article
Ulrike U. Ernemann, Eckart Grönewäller, Frank B. Duffner, Oezlem Guervit, Joerg Claassen, Martin D. Skalej
Influence of Geometric and Hemodynamic Parameters on Aneurysm Visualization during Three-Dimensional Rotational Angiography: An in Vitro Study
American Journal of Neuroradiology Apr 2003, 24 (4) 597-603;

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Influence of Geometric and Hemodynamic Parameters on Aneurysm Visualization during Three-Dimensional Rotational Angiography: An in Vitro Study
Ulrike U. Ernemann, Eckart Grönewäller, Frank B. Duffner, Oezlem Guervit, Joerg Claassen, Martin D. Skalej
American Journal of Neuroradiology Apr 2003, 24 (4) 597-603;
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