Technical Feasibility of Embolizing Aneurysms with Glue (n-butyl 2-cyanoacrylate): Experimental Study in Rabbits

Aneurysm 4. Partially embolized aneurysm without a coil framework.

A, After obtaining this preembolization angiogram, 40% glue was injected for 1 minute and 26 seconds under subtracted, real-time road-map fluoroscopy.

B–D, Frozen images of the early (B), middle (C), and late (D) phases show leakage of the cast along the wall.

E and F, Angiograms obtained immediately after embolization (E) and at 2-month follow-up (F) show persistent occlusion of the carotid artery.

Aneurysm 16. Complete embolization with a coil framework.

A and B, After obtaining the preembolization angiogram (A), an 8 x 20-cm GDC was introduced into the aneurysm to make a coil framework (B) and 28% glue was injected for 2 minutes and 3 seconds under subtracted, real-time road-map fluoroscopy.

C and D, Frozen images of the early (C) and late (D) phases.

E and F, Angiorams obtained immediately after embolization (E) and at 2-month follow-up (F) reveal persistent obliteration of the aneurysm.

Aneurysm 9. Partially embolized aneurysm after making a coil framework.

A–C, After obtaining a preembolization angiogram (A), an 8 × 20-cm GDC was introduced into the aneurysm to make a coil framework (B) and 50% glue was injected for 1 minute 35 seconds under subtracted, real-time road-map fluoroscopy (C). Glue could not be further injected probably because of the premature cast within the microcatheter.

D and E, Angiogram obtained immediately after embolization (D) shows a residual lumen within the aneurysm that appears smaller on the 2-month follow-up angiogram (E).