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OtherBRAIN

Glioblastoma Multiforme Causing Calvarial Destruction: An Unusual Manifestation Revisited

Vinay Gheyi, Ferdinand K. Hui, Egon M. Doppenberg, William Todd and William C. Broaddus
American Journal of Neuroradiology October 2004, 25 (9) 1533-1537;
Vinay Gheyi
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Ferdinand K. Hui
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Egon M. Doppenberg
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William Todd
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William C. Broaddus
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Article Figures & Data

Figures

  • Fig 1.
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    Fig 1.

    CT scans.

    A and B, Nonenhanced scans obtained at slightly different heights show a rounded heterogeneous mass in the right frontoparietal region (arrow).

    C, Higher section shows inward dural displacement (arrow) and overlying calvarial destruction, suggesting extra-axial extension of the mass.

  • Fig 2.
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    Fig 2.

    Bone window settings from the same nonenhanced CT study as in Figure 1 shows calvarial destruction (arrow).

  • Fig 3.
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    Fig 3.

    MR images demonstrate intra- and extra-axial locations of the mass eroding through the calvaria (arrow). Note inward displacement of the hypointense dura.

    A, T2-weighted image.

    B, T1-weighted image.

    C, Gadolinium-enhanced T1-weighted image.

  • Fig 4.
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    Fig 4.

    Sequential T2-weighted images demonstrate no definite gross violation of the dura.

  • Fig 5.
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    Fig 5.

    Tumor eroding through the bone before the bone flap was created.

  • Fig 6.
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    Fig 6.

    Epidural tumor leaving the dura macroscopically intact without substantial dural adherence.

  • Fig 7.
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    Fig 7.

    Macroscopically intact dura after the epidural portion of tumor was removed.

  • Fig 8.
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    Fig 8.

    Intracerebral component is visible and surrounded by normal cortex.

  • Fig 9.
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    Fig 9.

    Right parietal dura with tumor (arrows) on both sides of the dura (original magnification ×40).

  • Fig 10.
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    Fig 10.

    Right parietal intracerebral tumor (arrow). Image shows the GBM arising in the brain and growing outward as a mass outside the brain that penetrated the dura and the skull (original magnification ×20).

  • Fig 11.
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    Fig 11.

    Right parietal tumor shows positivity for immunoperoxidase staining against GFAP (original magnification ×40).

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American Journal of Neuroradiology: 25 (9)
American Journal of Neuroradiology
Vol. 25, Issue 9
1 Oct 2004
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Cite this article
Vinay Gheyi, Ferdinand K. Hui, Egon M. Doppenberg, William Todd, William C. Broaddus
Glioblastoma Multiforme Causing Calvarial Destruction: An Unusual Manifestation Revisited
American Journal of Neuroradiology Oct 2004, 25 (9) 1533-1537;

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Glioblastoma Multiforme Causing Calvarial Destruction: An Unusual Manifestation Revisited
Vinay Gheyi, Ferdinand K. Hui, Egon M. Doppenberg, William Todd, William C. Broaddus
American Journal of Neuroradiology Oct 2004, 25 (9) 1533-1537;
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