Article Figures & Data
Figures
- Fig 1.
Control subject aged 27 months. Maps of the brain at the level of the lateral ventricular bodies show the right parietal-occipital central white matter with ROIs in the frontoparietal, parietal-occipital, frontal central white matter and in the anterior and posterior corpus callosum.
A, EV1; B, EV2; C, EV3; D, trace ADC.; E, FA index.
F, Color-coded fiber orientation. Left-right, anterior-posterior, and superior-inferior directions are associated with pure red, green, and blue, respectively. Combinations of these colors represent oblique fibers.
- Fig 2.
PKU patient aged 25 months. Cerebral maps at the level of lateral ventricular bodies.
A, EV1.
B, EV2 increases in the bilateral frontal and parietal-occipital central parenchyma, more prominently in the right parietal-occipital central areas (arrows). High-EV2 area is more extensive in bilateral parietal-occipital central areas than in areas shown in Figure 1B.
C, High EV3 is prominent in parietal-occipital central areas, more on the right (arrows) than the left.
D, ADCs are diffusely increased, slightly in the bilateral frontal, right frontoparietal, and bilateral parietal-occipital central parenchyma (arrows); the difference is not significant.
E, FA is reduced in parietal-occipital central white matter, more on the right (arrows) than the left.
Tables
- TABLE 1:
Results of the Mann-Whitney rank-sum test in patients and control subjects older than 3 years
Position P Value EV1 EV2 EV3 ADC FA Frontoparietal central white matter .37 .49 .79 .64 .56 Parieto-occipital central white .37 .02 .04 .16 .02 Superiofrontal central white matter .43 1.00 .64 .87 .79 Anterior portion of corpus callosum .27 .10 .19 .13 .08 Posterior portion of corpus callosum .27 .71 .79 >.99 .96 - TABLE 2:
Results of the Mann-Whitney rank-sum test in patients and control subjects younger than 3 years
Position P Value EV1 EV2 EV3 ADC FA Frontoparietal central white matter .66 >.99 >.99 >.99 >.99 Parieto-occipital central white >.99 .38 .66 .38 .38 Superiofrontal central white matter .66 >.99 >.99 >.99 >.99 Anterior portion of corpus callosum .66 >.99 .66 .66 .66 Posterior portion of corpus callosum >.99 .38 .38 .19 .66
