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MR Imaging of a Posterior Mediastinal Ganglioneuroma: Fat as a Useful Diagnostic Sign

Sheila Duffy, Miral Jhaveri, Jennifer Scudierre, Elizabeth Cochran and Michael Huckman
American Journal of Neuroradiology November 2005, 26 (10) 2658-2662;
Sheila Duffy
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Miral Jhaveri
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Jennifer Scudierre
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Elizabeth Cochran
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Michael Huckman
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    Fig 1.

    A–C, Sagittal T1-weighted images (TR 366/TE 14), from right to left, showing a right paraspinal mass with predominant high T1 signal intensity and interspersed areas of intermediate signal intensity. The mass extends through the intervertebral foramina, causing widening of the foramina.

    D, Axial T1-weighted image (TR 366/TE 14) showing a right paraspinal mass that extends through the intervertebral foramina causing widening of the foramina and scalloping of the posterior margin of the vertebral body.

    E, Axial T2-weighted fast spin-echo image (TR 3400/TE 110) showing mild effacement of the right lateral aspect of the thecal sac without any significant compression.

    F and G, Sagittal fat-suppressed postcontrast T1-weighted images (TR 366/TE 14) show that the mass follows the signal intensity of the subcutaneous fat. There are interspersed areas of enhancement.

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    Fig 2.

    A, Microscopic picture demonstrating adipose tissue (short arrow), Schwann cells, lymphocytes (arrowhead), and ganglion cells (long arrow); original magnification 10×.

    B, On the left, S100 immunostain demonstrates that the tissue is composed predominantly of Schwann cells. On the right, Synaptophysin immunostain confirms the presence of ganglion cells (arrows); original magnification 20×.

    C, High-power picture of multinucleated ganglion cells (arrows); original magnification 40×.

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American Journal of Neuroradiology: 26 (10)
American Journal of Neuroradiology
Vol. 26, Issue 10
1 Nov 2005
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Cite this article
Sheila Duffy, Miral Jhaveri, Jennifer Scudierre, Elizabeth Cochran, Michael Huckman
MR Imaging of a Posterior Mediastinal Ganglioneuroma: Fat as a Useful Diagnostic Sign
American Journal of Neuroradiology Nov 2005, 26 (10) 2658-2662;

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MR Imaging of a Posterior Mediastinal Ganglioneuroma: Fat as a Useful Diagnostic Sign
Sheila Duffy, Miral Jhaveri, Jennifer Scudierre, Elizabeth Cochran, Michael Huckman
American Journal of Neuroradiology Nov 2005, 26 (10) 2658-2662;
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