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OtherSPINE

Inflammatory Pseudotumor in the Epidural Space of the Thoracic Spine: A Case Report and Literature Review of MR Imaging Findings

Ho Jun Seol, Sam Soo Kim, Ji Eun Kim, Sang Hyung Lee and Jun Yeon Won
American Journal of Neuroradiology November 2005, 26 (10) 2667-2670;
Ho Jun Seol
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Sam Soo Kim
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Ji Eun Kim
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Sang Hyung Lee
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Jun Yeon Won
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  • Fig 1.
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    Fig 1.

    Thoracic spine CT scan shows an epidural mass compressing the spinal cord without bony destruction.

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    Fig 2.

    MR imaging demonstrates the expansile epidural mass from T1 to T7, showing heterogeneous iso- and hyperintensity on the sagittal T2-weighted image (A) and homogeneous isointensity on the T1-weighted image (B). The postcontrast sagittal (C) and axial (D) images reveal a homogeneous enhancing lesion with cord compression. There is no abnormality in the adjacent bone.

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    Fig 3.

    Microscopically, there is a polymorphic infiltrate composed of plump myofibroblasts (arrows) and lymphoplasma cells in loose fibromyxoid stroma, suggesting inflammatory myofibroblastic tumor (hematoxylin and eosin, original magnification ×100).

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    Fig 4.

    A, Abundant inflammatory cells such as plasma cells (arrow) in rich vascular stroma are seen in some areas (hematoxylin and eosin, original magnification ×200.)

    B, Paucicellular area shows platelike collagen resembling scar tissue (hematoxylin and eosin, original magnification ×200).

Tables

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  • Characteristics of cases of inflammatory pseudotumors reported in the literature that originated in the spinal canal

    SourceAge (y)/SexLocationRelation with MeningesBony DestructionSignal Intensity on MR Images Compared with Spinal Cord
    T1-weightedT2-weightedContrast-enhanced
    Roberts et al, 1997 (1)58/FT9–T11EpiduralYesIsoHypoNR
    Aizawa et al, 2002 (3)46/MC3–C7IntramedullaryNoIsoHypoWell
    Jeon et al, 2005 (4)60/FLEtramedullary intraduralNRNRNRWell
    Hsieh and Lin, 1995 (5)37/MT5, T12–L1Extramedullary intraduralNoLowNRNR
    Eimoto et al, 1978 (6)37/MC4–C5Extramedullary intraduralNoNRNRNR
    Gilliard et al, 2000 (7)45/MC3–T2EpiduralYesIsoNRWell
    Hsiang et al, 1994 (8)57/MT12–T13Intra- and extraduralYesLowNRWell
    Roberts et al, 2001 (9)39/FT5–T6EpiduralNoIsoHypoNR
    Lee et al, 1998 (10)3/FC2–T10IntramedullaryNoNRNRWell
    Kilinc et al, 2002 (11)34/MT9–T12IntramedullaryNoLowHyperWell
    Despeyroux-Ewers et al, 2003 (12)22/FT9Extramedullary intraduralNoIsoHypoWell
    • Note.—Iso indicates isointensity; Hypo, hypointensity; NR, not reported.

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American Journal of Neuroradiology: 26 (10)
American Journal of Neuroradiology
Vol. 26, Issue 10
1 Nov 2005
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Cite this article
Ho Jun Seol, Sam Soo Kim, Ji Eun Kim, Sang Hyung Lee, Jun Yeon Won
Inflammatory Pseudotumor in the Epidural Space of the Thoracic Spine: A Case Report and Literature Review of MR Imaging Findings
American Journal of Neuroradiology Nov 2005, 26 (10) 2667-2670;

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Inflammatory Pseudotumor in the Epidural Space of the Thoracic Spine: A Case Report and Literature Review of MR Imaging Findings
Ho Jun Seol, Sam Soo Kim, Ji Eun Kim, Sang Hyung Lee, Jun Yeon Won
American Journal of Neuroradiology Nov 2005, 26 (10) 2667-2670;
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