Dilated Perivascular Spaces: Hallmarks of Mild Traumatic Brain Injury

American Journal of Neuroradiology

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Fig 1.
Axial high-convexity T2-weighted images (TE/TR = 119/7900) from younger (A–C) and older (D–F) subjects. Note numerous enlarged VRS in B–F and their absence in A.
A, 28-year-old control subject.
B, 20-year-old patient imaged 7 days after trauma.
C, 27-year-old patient imaged 1.5 years after trauma.
D, 40-year-old control subject.
E, 42-year-old patient imaged 7 days after trauma.
F, 47-year-old patient imaged 1.7 years after trauma.
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Fig 2.
Graph showing the correlation between the number of VRS and the age, expressed in years, in patients (squares) and control subjects (circles). VRS are associated with age (R = 0.69, P < .001) only in controls. Least-squares regression line indicates a significant linear relationship: no. of VRS = −4.9 + 0.250 (age in years). That is, the average increment is one VRS per 4-year increment of age.

Demographic data and trauma-related imaging findings in 24 patients with TBI

Patient/Age (y)/ Sex	Delay after TBI (d)	GCS Score	Cause of TBI	Trauma-Related MR Imaging Findings
1/35/F	1	15	MVA	Unremarkable
2/46/F	1	15	MVA	Unremarkable
3/31/F	1	15	Fall	Unremarkable
4/29/M	1	15	Fall	Subdural hematoma
5/33/M	1	15	MVA	Unremarkable
6/20/M	2	15	MVA	Unremarkable
7/30/M	2	15	BI	Unremarkable
8/42/M	2	15	Fall	Unremarkable
9/31/F	3	15	Fall	Unremarkable
10/30/M	3	15	Fall	Unremarkable
11/18/M	5	15	Fall	Unremarkable
12/20/M	7	15	Assault	Unremarkable
13/22/F	8	15	Fall	Unremarkable
14/26/F	9	15	Fall	Unremarkable
15/36/F	9	15	Fall	Unremarkable
16/36/M	31	15	BI	Contusion
17/37/M	46	14	Fall	Unremarkable
18/47/M	124	15	MVA	Contusion
19/20/F	396	15	BI	Contusion (old)
20/50/F	575	15	MVA	Unremarkable
21/48/F	635	15	MVA	Unremarkable
22/27/M	760	15	MVA	Unremarkable
23/43/M	1170	15	MVA	Unremarkable
24/46/M	5110	15	MVA	Unremarkable