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Research ArticleHead and Neck Imaging

MR Imaging of Salivary Duct Carcinoma

Ken Motoori, Yumiko Iida, Yuichirou Nagai, Seiji Yamamoto, Takuya Ueda, Hiroyuki Funatsu, Hisao Ito and Okamoto Yoshitaka
American Journal of Neuroradiology May 2005, 26 (5) 1201-1206;
Ken Motoori
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Yumiko Iida
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Yuichirou Nagai
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Seiji Yamamoto
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Takuya Ueda
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Hiroyuki Funatsu
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Hisao Ito
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Okamoto Yoshitaka
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    Fig 1.

    SDC in the left parotid gland of a 48-year-old man.

    A, T2-weighted image (4000/104 [TR/TE], coronal plane) shows a tumor with ill-defined margin. The tumor shows low (arrow) to moderately high signal intensity for the contralateral parotid gland.

    B, STIR image (4000/30, axial plane) also shows a hypointensity focus (arrow) in the tumor. The border of the tumor is invasive (arrowheads).

    C, T1-weighted image (400/9, axial plane) shows an isointense tumor.

    D, Third phase images on dynamic study (6.3/1.4, axial plane) show irregular enhancement. Marked enhanced area (region of interest 1), well-enhanced area (region of interest 2), and gradual upward enhanced area (region of interest 3) are detected.

    E, Signal intensity graph shows that the washout ratio of region of interest 1 is 35% (type A) and that of region of interest 2 is 13% (type B). Time–signal intensity curves of region of interest 3 show gradual upward enhancement (type C).

    F, Radical parotidectomy including facial nerve, mastoid tip, and skin was performed. Tumor extension from the cut specimen (arrowheads) is in good agreement with the MR images. The focus showing hypointensity on STIR and T2-weighted images and gradual upward enhancement on dynamic MR images corresponding to the fibrotic area (asterisk).

    G, The light-optic appearance (original magnification ×40) in region of interest 1 shows abundant atypical epithelial cells (white asterisks) with fibrotic stromata (black asterisks).

    H, The light-optic appearance (original magnification ×40) in region of interest 2 shows atypical epithelial cells (white asterisks) with fibrotic stromata and many foci of comedonecrosis (double asterisks).

    I, The light-optic appearance (original magnification ×40) in region of interest 3 shows dense fibrotic tissue with cellular components (white asterisk).

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    Fig 2.

    SDC in the left parotid gland of a 52-year-old man. He has ipsilateral metastatic lymph nodes and contralateral reactive lymph nodes.

    A, Fat-suppression T1-weighted image (340/20, axial plane) shows multiple cervical lymphadenopathies. Metastatic lymph node (arrow) is >10 mm in minimal axial diameter. Reactive lymph node (arrowhead) is <10 mm in minimal axial diameter.

    B, On diffusion-weighted image (spin-echo single-shot echo-planar sequence with b factors of 0 and 1000 s/mm2), both lymph nodes show high signal intensity. The ADC value of the metastatic lymph node (region of interest 1) is 1.23 × 10−3 mm2/s and that of the reactive lymph node is 0.90 × 10−3 mm2/s.

    C, Signal intensity graph shows that the washout ratio of region of interest 1 is 2% (type B) and that of region of interest 2 is 48% (type A).

Tables

  • Figures
  • MR features of 9 patients with salivary duct carcinoma

    PatientAge (yr)SexSiteSize (cm)LNsTICsADC Value (×10−3 mm2/s)
    153Mrt parotid3.2YesB (11–25)C
    281Mrt parotid2.1NoB (22)C
    337Mrt parotid3.4YesB (11)CD1.03
    465Frt parotid4.0NoB (12)D1.06
    583Mrt parotid3.4NoC1.43
    652Mlt parotid3.8YesB (27)C1.15
    760Mrt parotid2.1YesB (1)1.20
    848Mlt parotid4.5NoA (35)B (13)C1.18
    983Flt submandibular2.8YesB (19)1.05
    • Note.—LNs indicates lymph nodes, TICs, time-signal intensity curves, Washout ratio (WR) in parentheses, expressed as percentage.

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American Journal of Neuroradiology: 26 (5)
American Journal of Neuroradiology
Vol. 26, Issue 5
1 May 2005
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Cite this article
Ken Motoori, Yumiko Iida, Yuichirou Nagai, Seiji Yamamoto, Takuya Ueda, Hiroyuki Funatsu, Hisao Ito, Okamoto Yoshitaka
MR Imaging of Salivary Duct Carcinoma
American Journal of Neuroradiology May 2005, 26 (5) 1201-1206;

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MR Imaging of Salivary Duct Carcinoma
Ken Motoori, Yumiko Iida, Yuichirou Nagai, Seiji Yamamoto, Takuya Ueda, Hiroyuki Funatsu, Hisao Ito, Okamoto Yoshitaka
American Journal of Neuroradiology May 2005, 26 (5) 1201-1206;
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  • Diagnosing common parotid tumours with magnetic resonance imaging including diffusion-weighted imaging vs fine-needle aspiration cytology: a comparative study
  • Salivary duct carcinoma of the parotid gland: clinical and MR features in six patients
  • Diffusion-Weighted Echo-Planar MR Imaging of Primary Parotid Gland Tumors: Is a Prediction of Different Histologic Subtypes Possible?
  • MRI of chronic sclerosing sialoadenitis
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