Article Figures & Data
Figures
- Fig 1.
Segmentation procedure. After manually tracing the in-plane boundaries, histogram-based segmentation was used to categorize the region of interest into CSF (black), gray matter (gray), and white matter (white). Only pixels of gray matter are counted to exclude the region of gliosis and atrophy.
- Fig 2.
For each subject, two sides of HV are divided into large and small sides. In the control group, the asymmetry index (AIv) is 2.2% on average. The plot shows different relationships among three groups in large and small sides. The interaction between groups and sides is statistically significant (P < .01).
- Fig 3.
For each subject, two sides of NAA/(Cho + Cr) ratios are divided into large and small sides. The asymmetry index (AIs) scatters in a wide range. In the control group, the AIs is 0.77 on the average. The plot shows that the relationships among three groups in large and small sides are quite parallel. There is a trend of lowering NAA/(Cho + Cr) ratios in TLE + FC, but no statistical interaction between groups and sides was found (P = .272).
Tables
Groups Number (male/female) Age at MR imaging (yrs) mean ± std (range) Control 16 (10/6) 9.1 ± 3.6 (3–15) TLE + FC 22 (12/10) 8.8 ± 3.5 (3–15) TLE 17 (6/11) 8.2 ± 3.9 (1.5–14) Note.—TLE indicates temporal lobe epilepsy; FC, febrile convulsion.
Control TLE + FC TLE AIv 2.32 ± 1.58% 9.22 ± 6.79% 6.79 ± 5.73% AIs 8.47 ± 5.08% 18.10 ± 16.24% 16.81 ± 10.02% Note.—TLE indicates temporal lobe epilepsy; FC, febrile convulsion; AIv, volume asymmetry index; and AIs, spectroscopy asymmetry index. Both AIv and AIs are statistically smaller in Control than TLE + FC and TLE (P < .01 with AIv and P < .05 with AIs). No significant difference exists between TLE + FC and TLE either in AIv or AIs. As to conditions of normal hippocampal volume at both sides in epileptic groups, AIv culls 5/8 and 4/10 in TLE + FC and TLE, respectively. On the other hand, AIs picks out 1/6 and 1/4 of the subjects with bilaterally normal NAA/(Cho + Cr) in TLE + FC and TLE, respectively.
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