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OtherPediatric Neuroimaging

Contribution of Fetal MR Imaging in the Prenatal Diagnosis of Zellweger Syndrome

F. Mochel, A.-G. Grébille, A. Benachi, J. Martinovic, F. Razavi, D. Rabier, I. Simon, N. Boddaert, F. Brunelle and P. Sonigo
American Journal of Neuroradiology February 2006, 27 (2) 333-336;
F. Mochel
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A.-G. Grébille
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A. Benachi
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J. Martinovic
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F. Razavi
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D. Rabier
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I. Simon
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N. Boddaert
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F. Brunelle
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P. Sonigo
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    Fig 1.

    Case 1. Axial T2-weighted MR images show bilateral ventriculomegaly as well as large cavum. Abnormally small cerebral convolutions predominate in the frontal and perisylvian cortex (A) and periventricular leukodystrophy predominates in the frontal area. Note bilateral germinolytic cysts in the subependymal areas (B).

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    Fig 2.

    Case 2. Axial T2-weighted MR images reveal, as in case 1, bilateral ventricular enlargement, frontal abnormalities of the white matter, and polymicrogyria predominating in the frontal, perisylvian cortex with large sylvian valley (A) and bilateral periventricular pseudocysts (B).

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    Fig 3.

    Case 2. Coronal T2-weighted MR image shows large cavum and bilateral subependymal pseudocysts (A). Postmortem coronal section confirms the micropolygyric pattern predominating in the frontal and perisylvian cortex (B).

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American Journal of Neuroradiology: 27 (2)
American Journal of Neuroradiology
Vol. 27, Issue 2
February, 2006
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F. Mochel, A.-G. Grébille, A. Benachi, J. Martinovic, F. Razavi, D. Rabier, I. Simon, N. Boddaert, F. Brunelle, P. Sonigo
Contribution of Fetal MR Imaging in the Prenatal Diagnosis of Zellweger Syndrome
American Journal of Neuroradiology Feb 2006, 27 (2) 333-336;

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Contribution of Fetal MR Imaging in the Prenatal Diagnosis of Zellweger Syndrome
F. Mochel, A.-G. Grébille, A. Benachi, J. Martinovic, F. Razavi, D. Rabier, I. Simon, N. Boddaert, F. Brunelle, P. Sonigo
American Journal of Neuroradiology Feb 2006, 27 (2) 333-336;
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