Research ArticleSPINE
Bone Marrow Diffusion Measures Correlate with Dementia Severity in HIV Patients
A.B. Ragin, Y. Wu, P. Storey, B.A. Cohen, R.R. Edelman, L.G. Epstein and S. Gartner
American Journal of Neuroradiology March 2006, 27 (3) 589-592;
A.B. Ragin
Y. Wu
P. Storey
B.A. Cohen
R.R. Edelman
L.G. Epstein

References
- ↵McArthur J, Hoover D, Bacellar H, et al. Dementia in AIDS patients: incidence and risk factors: Multicenter AIDS Cohort Study. Neurology 1993;43:2245–52
- ↵Williams KC, Hickey WF. Central nervous system damage, monocytes and macrophages, and neurological disorders in AIDS. Annu Rev Neurosci 2002;25:537–62
- ↵Gartner S. HIV infection and dementia. Science 2000;287:602–604
- ↵Marder K, Albert SM, McDermott MP, et al. Inter-rater reliability of a clinical staging of HIV-associated cognitive impairment. Neurology 2003;60:1467–73
- ↵Price RW, Brew BJ. The AIDS dementia complex. J Infect Dis 1988;158:1079–83
- ↵Karnofsky DA, Abelman WH, Craver LF, et al. The use of nitrogen mustards in the palliative treatment of carcinoma. Cancer 1948;1:634–56
- ↵DPTools. Version 1.4. Paris: INFORMAG;2001
- ↵Basser PJ, Pierpaoli C. A simplified method to measure the diffusion tensor from seven MR images. Magn Reson Med 1998;39:928–34
- ↵McArthur JC, McDermott MP, McClernon D, et al. Attenuated central nervous system infection in advanced HIV/AIDS with combination antiretroviral therapy. Arch Neurol 2004;61:1687–96
- ↵Beaulieu C. The basis of anisotropic water diffusion in the nervous system: a technical review. NMR Biomed 2002;15:435–55
- ↵Eustace S, McGrath D, Albrecht M, et al. Clivical marrow changes in AIDS: findings at MR imaging. Radiology 1994;193:623–27
- ↵Geremia GK, McCluney KW, Adler SS, et al. The magnetic resonance hypointense spine of AIDS. J Comput Assist Tomogr 1990;14:785–89
- ↵Schneider DR, Picker LJ. Myelodysplasia in the acquired immune deficiency syndrome. Am J Clin Pathol 1985;84:144–52
- Kaloutsi V, Kohlmeyer U, Maschek H, et al. Comparison of bone marrow and hematological findings in patients with human immunodeficiency virus infection and those with myelodysplastic syndromes and infectious diseases. Am J Clin Pathol 1994;101:123–29
- ↵Titius BR, Thiele J, Schaefer H, et al. Ki-S1 and proliferating cell nuclear antigen expression of bone marrow macrophages: immunohistochemical and morphometric study including reactive (inflammatory) myelitis, secondary aplastic anemia, AIDS, myelodysplastic syndromes and primary (idiopathic) osteomyelofibrosis. Acta Haematol 1994;91:144–49
- ↵Weiser B, Burger H, Campbell P, et al. HIV type 1 RNA expression in bone marrows of patients with a spectrum of disease. AIDS Res Hum Retroviruses 1996;12:1551–58
- ↵Wintrobe MM, Lee GR, Boggs DR, et al. Origin and development of the blood and bloodforming tissues. In: Clinical hematology. 8th ed. Philadelphia: Lea & Febiger;1981 :52
- ↵
- ↵Mulkern RV, Huang JS, Vajapeyam S, et al. Fat fractions and spectral T2 values in vertebral bone marrow in HIV- and non-HIV-infected men: a 1H spectroscopic imaging study. Magn Reson Med 2004;52:552–58
- ↵Loevner LA, Tobey JD, Yousem DM, et al. MR imaging characteristics of cranial bone marrow in adult patients with underlying systemic disorders compared with healthy control subjects. AJNR Am J Neuroradiol 2002;23:267–72
- ↵Takagi S, Tsunoda S, Tanaka O. Bone marrow involvement in lymphoma: the importance of marrow magnetic resonance imaging. Leuk Lymphoma 1998;29:515–22
- ↵Pulliam L, Gascon R, Stubblebine M, et al. Unique monocyte subset in patients with AIDS dementia. Lancet 1997;349:692–95
- ↵Wiley C, Achim C. Human immunodeficiency virus encephalitis is the pathological correlate of dementia in acquired immunodeficiency syndrome. Ann Neurol 1994;36:673–76
- ↵Glass JD, Fedor H, Wesselingh SL, et al. Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia. Ann Neurol 1995;38:755–62
- ↵Conant K, Garzino-Demo A, Nath A, et al. Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia. Proc Natl Acad Sci U S A 1998;95:3117–21
- ↵Conant K, McArthur JC, Griffin DE, et al. Cerebrospinal fluid levels of MMP-2, 7 and 9 are elevated in association with HIV-dementia. Ann Neurol 1999;46:391–98
- ↵Nath A, Conant K, Chen P, et al. Transient exposure to HIV-1 Tat protein results in cytokine production in macrophages and astrocytes: a hit and run phenomenon. J Biol Chem 2001;274:17098–102
- ↵Kaul M, Garden GA, Lipton SA. Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 2001;410:988–94
- ↵Gartner S, Liu Y. Insights into the role of immune activation in HIV neuropathogenesis. J of Neurovirol 2002;8:69–75
- ↵
In this issue
Advertisement
A.B. Ragin, Y. Wu, P. Storey, B.A. Cohen, R.R. Edelman, L.G. Epstein, S. Gartner
Bone Marrow Diffusion Measures Correlate with Dementia Severity in HIV Patients
American Journal of Neuroradiology Mar 2006, 27 (3) 589-592;
0 Responses
Jump to section
Related Articles
- No related articles found.
Cited By...
This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.
More in this TOC Section
Similar Articles
Advertisement