Research ArticlePEDIATRICS
Hypothalamic Hamartomas: Correlation of MR Imaging and Spectroscopic Findings with Tumor Glial Content
D.R. Amstutz, S.W. Coons, J.F. Kerrigan, H.L. Rekate and J.E. Heiserman
American Journal of Neuroradiology April 2006, 27 (4) 794-798;
D.R. Amstutz
S.W. Coons
J.F. Kerrigan
H.L. Rekate

References
- ↵Judge D, Kulin H, Page R, et al. Hypothalamic hamartoma: a source of luteinizing-hormone-releasing factor in precocious puberty. N Engl J Med 1977;296:7–10
- Inoue H, Kanazawa H, Kohga H, et al. Hypothalamic hamartoma: anatomic, immunohistochemical, and ultrastructural features. Brain Tumor Pathol 1995;12:45–51
- ↵Diebler C, Ponsot G. Hamartomas of the tuber cinereum. Neuroradiology 1983;25:93–101
- ↵Veldueza J, Cristante L, Dammann O, et al. Hypothalamic hamartomas: with special reference to gelastic epilepsy and surgery. Neurosurgery 1994;34:949–58
- ↵Grossman R, Yousem D. Neuroradiology: The Requisites. 2nd ed. Philadelphia, Pa: Mosby;2003 :548–50
- ↵Osborn Anne. Diagnostic Imaging:. Brain. Vol. II. Salt Lake City, Utah: Amirsys;2004 :2:12
- ↵Martin D, Seeger U, Ranke M, et al. MR imaging and spectroscopy of a tuber cinereum hamartoma in a patient with growth hormone deficiency and hypogonadotropic hypogonadism. AJNR Am J Neuroradiol 2003;24:1177–80
- ↵Barkovich A. Intracranial, Orbital and Neck Tumors of Childhood: Pediatric Neuroimaging. Philadelphia, Pa: Lippincott Williams & Wilkins;2000 :443–580
- ↵Freeman JL, Coleman LT, Wellard RM, et al. MR imaging and spectroscopic study of epileptogenic hypothalamic hamartomas: analysis of 72 cases. AJNR Am J Neuroradiol 2004;25:450–62
- ↵Richter RB. True hamartoma of the hypothalamus associated with pubertas praecox. J Neuropathol Exp Neurol 1951;10:368–83
- ↵Kahane P, Tassi L, Hoffmann D. Cries dacrystiques et hamartome hypothlamique: a propos d’une observation video-EEG. Epilepsies 1994;6:259–79
- ↵Northfield D, Russell D. Pubertas praecox due to hypothalamic hamartoma: report of two cases surviving surgical removal of the tumour. J Neurol Neurosurg Psychiatry 1967;30:166–73
- ↵Georgakoulias N, Vize C, Jenkins A, et al. Hypothalamic hamartomas causing gelastic epilepsy: two cases and a review of the literature. Seizure 1998;7:167–71
- ↵Wakai S, Nikaido K, Nihira H, et al. Gelastic seizure with hypothalamic hamartoma: proton magnetic resonance spectrometry and ictal electroencephalographic findings in a 4-year-old girl. J Child Neurol 2002;17:44–46
- ↵Tasch E, Cendes F, Li L, et al. Hypothalamic hamartomas and gelastic epilepsy: a spectroscopic study. Neurology 1998;51:1046–50
- ↵
- ↵Krieger MD, Panigrahy A, McComb JG, et al. Differentiation of choroid plexus tumors by advanced magnetic resonance spectroscopy. Neurosurg Focus 2005;15:18
- ↵
- ↵Urenjak J, Williams S, Gadian D, et al. Proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types. J Neurosci 1993;13:981–89
- ↵Ross B. Biochemical considerations in 1H spectroscopy: glutamate and glutamine—myo-inositol and related metabolites. NMR Biomed 1991;4:59–63
- ↵Miller BL. A review of chemical issues in 1H NMR spectroscopy: N-acetyl-L-aspartate, creatine and choline. NMR Biomed 1991;4:47–52
- ↵Kim JP, Lentz MR, Westmoreland SV, et al. Relationships between astrogliosis and 1H MR spectroscopic measures of brain choline/creatine and myo-inositol/creatine in a primate model. AJNR Am J Neuroradiol 2005;26:752–59
- ↵Strange K, Emma F, Paredes A, et al. Osmoregulatory changes in myo-inositol content and Na+/myo-inositol cotransport in rat cortical astrocytes. Glia 1994;12:35–43
- ↵Castillo M, Smith JK, Kwock L. Correlation of myo-inositol levels and grading of cerebral astrocytomas. AJNR Am J Neuroradiol 2000;21:1645–49
- ↵Saraf-Lavi E, Bowen BC, Pattany PM, et al. Proton MR spectroscopy of gliomatosis cerebri: case report of elevated myoinositol with normal choline levels. AJNR Am J Neuroradiol 2003;24:946–51
- ↵Fernando KTM, McLean MA, Chard DT, et al. Elevated white matter myo-inositol in clinically isolated syndromes suggestive of multiple sclerosis. Brain 2004;127:1361–69
- ↵
- ↵Robertson NJ, Lewis RH, Cowan FM, et al. Early increases in brain myo-inositol measured by proton magnetic resonance spectroscopy in term infants with neonatal encephalopathy. Pediatr Res 2001;50:692–700
- ↵Jones RS, Waldman AD. 1H-MRS evaluation of metabolism in Alzheimer’s disease and vascular dementia. Neurol Res 2004;26:488–95
- ↵Londono A, Castillo M, Armano D, et al. Unusual MR spectroscopic imaging pattern of an astrocytoma: lack of elevated choline and high myo-inositol and glycine levels. AJNR Am J Neuroradiol 2003;24:942–45
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D.R. Amstutz, S.W. Coons, J.F. Kerrigan, H.L. Rekate, J.E. Heiserman
Hypothalamic Hamartomas: Correlation of MR Imaging and Spectroscopic Findings with Tumor Glial Content
American Journal of Neuroradiology Apr 2006, 27 (4) 794-798;
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